Hemex Health, Inc.

Inovise Medical, Inc.

Hewlett-packard Company

Covidien LP

Case Western Reserve University

Hewlett-packard Corporation

Nellcor Puritan Bennett Ireland

Innovise Medical, Inc.

Peter M Galen

Umut Atakan Gurkan

Joshua King Hoyt

Brian T Grimberg

James Daren Bledsoe

James Thorne

Daniel E Grupp

William E Saltzstein

Jered H Wikander

Martin Baumer

Arwa Fraiwan

Muhammad Noman Hasan

Paul Stanley Addison

David John Sayler

Susan R Hart

Steven M Goss

Ronald H Selvester

Tyler Witte

Joseph C Solomon

Dean Montgomery

Peter T Bauer

Steven A Mahoney

Robert J Deissler

Robert A Warner

Lawrence Hileman

Ariane Elizabeth Erickson

David Richard Bell

Matthew Christian Lind

D'Arbra Blankenship

James Nicholas Watson

David Lynn Burton

Patricia A Arand

Scott McGonigle

David B Swedlow

Daniel J Powers

Jagtar Singh Saroya

Jeffrey C Osborne

Damon J Coffman

Kent D Wilken

Patti A Arand

A diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The sample can be processed for data collection and analysis to provide interpretative results indicative of a disorder, condition, disease or infection of the patient. For example, the data collection and analysis can determine one or more hemozoin characteristics.

Malaria species detection

A system for monitoring autoregulation includes an oxygen saturation sensor configured to obtain an oxygen saturation signal indicative of an oxygen saturation of a patient. The system also includes a controller having a processor configured to receive a blood pressure signal indicative of a blood pressure of the patient and the oxygen saturation signal, determine a change in the oxygen saturation signal and a change in the blood pressure signal over a period of time, and provide an indication that the patient's autoregulation is intact if the oxygen saturation changes by more than an oxygen saturation threshold and if the blood pressure changes by less than a blood pressure threshold during the period of time.

Systems and methods of monitoring autoregulation

Electrophoresis is used to identify presence of a target compound in a patient sample based on a charge state of the compound and a label. The charge state of the compound correlates to a total net charge of a binder conjugated to the compound. The bound complex or 'bound complex' with the label is then applied to the electrophoresis substrate. An electric potential is applied to the substrate for a time period and causes the labeled bound complex to migrate toward the electrode with opposite charge of the labeled bound complex at a migration velocity to form a migration pattern over the time period. At some time during or at the end of the time period, the labeled bound complex produces a bound complex band as a result of its migration across the substrate. The presence of the compound is identified based on the labeled bound complex band and one or both of the migration pattern and the migration velocity.

Using electrophoresis for disease detection based on controlled molecular charge

A diagnostic system that includes a cartridge and a reader is discussed herein. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as an electrophoresis detection system that uses electrophoresis testing to identify and quantify various components of the blood sample. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disorder, condition, disease, or infection of the patient.

Diagnostics systems and methods

A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as an electrophoresis detection system that uses electrophoresis testing to identify and quantify various components of the blood sample. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disorder, condition, disease and/or infection of the patient.

A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as a magneto-optical system that measures a light transmission differential through the patient sample in varying magnetic fields. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disease, infection and/or condition of the patient.

Diagnostic cartridge

A diagnostic system detects and/or measures hemoglobin variants in blood of subject, such as HbA1c, to determine blood glucose concentration in the subject.

Diagnostic system for hemoglobin analysis

External sonication, which is a technique by which ultrasonic energy is applied externally to a cartridge containing the sample, is contemplated herein. External sonication can be performed by a sonicator external to a sample contained within a cartridge. The cartridge can include sonication particles to enhance sonication or cavitation within the sample. A sonication algorithm can also be used to increase sonication efficiency.

External sonication

Growing community of inventors

McMinnville, OR, United States of America

Peter M Galen