Bio-rad Laboratories, Inc.

Sport Maska Inc.

Artisent, LLC

Warrior Sports, Inc.

Opus Ksd Inc.

Gnubio, Inc.

Keurig, Inc.

Peter L Stokes

David Charles Rogers

Duco W Noordzij

Charles H Rogers

Sepehr Kiani

David H Tracy

Leonard Manfred Koenig

Edward R Hall

Tony Hung

Aaron Weber

Julia Z Sharpe

Kenneth S Danielson

Jon B Taylor

David G Honan

Karl T Winkler

Brendan J Duffy

Methods for deploying a fastener to close an incision or wound involve exposing the inner surface of each opposing side of the incision and inserting down into the exposed inner surfaces from above the fastener.

Deploying fasteners

Systems and methods are provided for determining a velocity or an inflation rate of a droplet in a microfluidic channel. The droplet is exposed to two or more temporally separated flashes of light, each flash including light of one wavelength band, and imaged using a detector configured to distinguish light in the wavelength bands. Two or more images of the droplet are acquired, each corresponding to one of the flashes, and all within a single video frame or photographic exposure. The images can be processed separately and the position or size of the droplet in each image is calculated. A velocity or inflation rate is then determined by dividing the change in position or size by the amount of time allowed to pass between the flashes.

Low cost optical high speed discrete measurement system

Methods and systems for controlling fluid flow through a cartridge for use in an assay of a fluid sample for detection of a target analyte. In one aspect, the cartridge includes a microfluidic device having a network of microfluidic channels, one or more reservoirs and one or more actuatable valves for controlling fluid flow from the reservoirs through the microfluidic channels. In some embodiments, the valve includes a deformable membrane movable between a closed configuration in which the membrane seals against the microfluidic device inhibiting fluid flow and an open configuration moved away from the microfluidic device to allow fluid flow through the microfluidic channels. Other valve embodiments utilize frangible membranes or user-removable membrane.

Microfluidic cartridge devices and methods of use and assembly

The present invention generally pertains to a system, method and kit for the detection and measurement of spectroscopic properties of light from a sample, or the scalable detection and measurement of spectroscopic properties of light from each sample present among multiple samples, simultaneously, wherein the system comprises: an optical train comprising a dispersing element; and an image sensor. The light detected and measured may comprise light scattered from a sample, emitted as chemiluminescence by a chemical process within a sample, selectively absorbed by a sample, or emitted as fluorescence from a sample following excitation.

Scalable spectroscopic detection and measurement

A headgear adjustment mechanism is provided that includes a worm having a central axis of rotation, a first headband element, a second headband element, a spur gear, and a housing. The first headband element includes (i) a worm rack disposed in operative engagement with the worm, and (ii) a first pinion rack. The second headband element includes a second pinion rack. The spur gear is disposed in simultaneous operative engagement with the first pinion rack and the second pinion rack, and the housing at least partially encloses the first and second headband elements. During operation of the adjustment mechanism, rotation of the worm about the axis of rotation causes the first headband element and the second headband element to translate in opposite directions with respect to the worm, thereby adjusting a fit of the headgear.

Worm drive adjustment for headgear suspension

A tissue fastener includes a bridge section and two cannulated leg sections. The tissue fastener is a single piece of material, and the material can be a bioabsorbable material. Each of the two leg sections can include at least one barb for resisting dislodgement from tissue after the fastener is inserted into tissue. The bridge can be flexible, and the leg sections can receive needles to allow insertion of the fastener into tissue from above a surface of the tissue. Various insertion devices and mechanisms are possible to deploy the fastener into a wound in a patient's skin from above the surface of and generally perpendicular to the skin.

Tissue fasteners and related insertion devices, mechanisms, and methods

Worm gear adjuster

A protective sport helmet, such as for lacrosse, includes a hard shell portion, a lining portion, and an adjustment mechanism. The inner side of the adjustment mechanism includes an adjustment protective pad. Together, the lining portion and the inner surface of the adjustment protective pad define an interior region of the helmet wherein the user's head is introduced. The adjustment mechanism includes a lower rear shell portion having a clutching mechanism that allows the user to manually adjust the size of the interior region via a strapping system of the helmet to couple snugly around the user's head. The clutching mechanism also prevents the interior region from being easily altered in the absence of manual adjustment to the adjustment mechanism. The strap includes a hard end material that engages the adjustment mechanism and a flexible, durable and tough material that conforms to a wearer's head.

Helmet adjustment system

A protective sport helmet, such as for lacrosse, includes a hard shell portion, a lining portion, and an adjustment mechanism. The inner side of the adjustment mechanism includes an adjustment protective pad. Together, the lining portion and the inner surface of the adjustment protective pad define an interior region of the helmet wherein the user's head is introduced. The adjustment mechanism includes a lower rear shell portion having a clutch mechanism that allows the user to manually adjust the size of the interior region via a strapping system of the helmet to couple snugly around the user's head. The clutching mechanism can prevent the interior region from being easily altered in the absence of manual adjustment to the adjustment mechanism. The strap includes a hard end material that engages the adjustment mechanism and a flexible, durable and tough material that conforms to a wearer's head.

An adjustment mechanism for a helmet. A first sliding surface is defined in a first portion of the helmet and includes an opening. A second sliding surface is defined in a second portion of the helmet. Two spaced apart arms extend from the second sliding surface. The first and second sliding surfaces are in sliding engagement with one another with the arms sliding within the opening. A lever is pivotally connected to the first portion in proximity of the opening and pivotable between a locked position and an unlocked position. The lever has a series of regularly spaced apart parallel teeth which in the locked position protrude through the opening with at least a selected one of the teeth being engageable between the two spaced apart arms to prevent the first and second sliding surfaces from sliding relative to one another.

Growing community of inventors

Boston, MA, United States of America

Peter L Stokes