The United States of America, As Represented by the Secretary, Department of Health and Human Services

Water Rower (uk) Ltd

Waterrower Inc.

Peter King

Frederick D Quinn

Manon Deslauriers

Frederick Quinn

Kristin A Birkness

David S Beall

Chris Footner

An illumination device for directing light into a transparent fluid tank of a fluid-resistance exercise machine is disclosed. The device can be coupled with an exterior surface of the tank and includes a light source oriented to project light through a surface and into a region of the fluid tank where the light can be observed by a user of the machine during operation, especially when a rotary device disturbs the fluid to generate the fluid resistance effect. The illumination device can include a control unit having a processor and a communication device, where the communication device receives an exercise-related parameter relayed during operation of the exercise machine. In response the control unit can dynamically adjust a quality of the light as a function of the received parameter, such as heartrate, output, resistance, time, distance, or speed.

Systems and methods for dynamically lighting a fluid-resistance exercise machine

An exercise machine assembly provides a fluid-based resistance force and allows a user to exert a force against the resistance force. A fluid displacement device is coupled to the exercise machine assembly and rotatably driven by the force exerted by the user. A fluid container has a hollow body enclosing the fluid displacement device, allowing for the fluid displacement device to rotate therein, and encloses a fluid. The fluid container includes an inner reservoir and an outer reservoir that cause the fluid-based resistance force to vary based on amounts of fluid in the inner and outer reservoirs, respectively. Further, the inner reservoir has one or more openings through which fluid can flow from either of the inner reservoir or the outer reservoir to the other.

Exercise machine having fluid container with adjustable water levels

Provided herein is an in vitro granuloma model and methods of its use. Methods of detecting and/or diagnosing latent tuberculosis in a subject are also provided, as are latency-specific antigens (and antibodies thereto), such as &#x3b1;-crystallin, and methods of identifying and using such molecules. Also provided are immunostimulatory compositions, for instance for use in eliciting an immune response in a subject, such as an immune response to a latent tuberculosis infection. Kits for carrying out the provided methods are also described.

Latent human tuberculosis model, diagnostic antigens, and methods of use

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Warren, RI, United States of America

Peter King