Elekta Ab (publ)

Peter Kimstrand

David Andreas Tilly

Nina Terese Tilly

Stella Riad

Jens Olof Sjölund

Jonas Anders Adler

Markus Eriksson

Linn Öström

Petter Ericson

Klas Marcks Von Würtemberg

Klas Mareks Von Würtemberg

Techniques for adjusting radiotherapy treatment for a patient in real time are provided. The techniques include operations comprising: obtaining, during delivery of a radiotherapy treatment fraction to a patient, one or more images of the patient at a first rate; generating patient motion information at a second rate based on the one or more images obtained at the first rate; receiving, during delivery of the radiotherapy treatment fraction, radiotherapy treatment device settings at a third rate; computing, during delivery of the radiotherapy treatment fraction, dose delivered to the patient with a first level of accuracy based on the generated patient motion information and the radiotherapy treatment device settings; and determining, during delivery of the radiotherapy treatment fraction, a real-time measure of accumulated dose delivered to the patient with a second greater level of accuracy than the first level of accuracy using one or more prior dose computations.

Adaptive dose accumulation algorithm

Techniques for adjusting radiotherapy treatment for a patient in real time are provided. The techniques include retrieving a reference plan that includes three-dimensional (3D) volume representation of information for the patient and a plurality of radiotherapy beam delivery segments; identifying a first portion of the 3D volume representation of information for a first beam delivery segment of the plurality of radiotherapy beam delivery segments that includes a volumetric portion of a target irradiated by the first beam delivery segment; accessing a deformation model representing patient deformation during a radiotherapy treatment fraction; deforming the first portion of the 3D volume representation of information based on the deformation model; and updating one or more parameters of a radiotherapy treatment device based on the deformed first portion of the 3D volume representation of information.

Geometry-based real-time adaptive radiotherapy

Techniques for adjusting radiotherapy treatment for a patient in real-time are provided. The techniques include determining a patient anatomy at a first time within a given radiotherapy treatment fraction after a radiotherapy treatment dose has been delivered by a radiotherapy device; retrieving a reference patient anatomy for the given radiotherapy treatment fraction that indicates a prescribed dose parameter to be delivered within the given radiotherapy treatment fraction; comparing the patient anatomy at the first time with the reference patient anatomy during the given radiotherapy treatment fraction; and based on the comparison of the patient anatomy at the first time with the reference patient anatomy, adjusting a parameter of the radiotherapy device to change an amount of radiotherapy treatment dose delivered at a second time, following the first time, within the given radiotherapy treatment fraction in accordance with the prescribed dose parameter to be delivered within the given radiotherapy treatment fraction.

Dose guided real-time adaptive radiotherapy

Systems and methods for calculating radiotherapy dose distribution are provided. The systems and methods include operations for receiving data representing at least one of particle trajectories or a dose deposition pattern in a simulated delivery of a radiotherapy plan; applying a dose calculation process to the received data to generate a first radiotherapy dose distribution having a first level of detail; and processing the first radiotherapy dose distribution using a trained machine learning technique to generate a second radiotherapy dose distribution having a second level of detail that enhances the first level of detail.

Computing radiotherapy dose distribution

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Uppsala, Sweden

Peter Kimstrand