Beckman Instruments, Inc.

Peter Kan

Wing S Pang

Dobson M Okawa

George K Shibata

Richard C Meyer

Wings S Pang

A system for analyzing a chemical reaction provides control of the temperature and volume of the reagents to improve the accuracy and precision in quantitative measurements of specific proteins and other immunochemistries in body fluids. The reaction occurs in a cuvette within a nephelometric optics module. A sensor senses the temperatures of reaction buffer liquids as they flow into the cuvette, and a heat exchanging device increases or decreases the temperatures of the buffer liquids. A control circuit responsive to the temperature sensor controls the heat exchanging device to maintain the temperature of the buffer liquids and the cuvette within a selected temperature range. The system may also include a sample pickup station, a sample probe for withdrawing a selected sample from the sample pickup station, a sample preparation station, and transport device for carrying said sample from the sample preparation station to the reaction cuvette. The system may include an antibody pickup station, an antibody probe for withdrawing an antibody from the antibody pickup station, an antibody preparation station, and antibody transport device for carrying the antibody from the antibody preparation station to the reaction cuvette.

Automatic immunochemistry analyzing apparatus and method

A system for analyzing a chemical reaction provides control of the temperature and volume of the reagents to improve the accuracy and precision in quantitative measurements of specific proteins and other immunochemistries in body fluids. The reaction occurs in a cuvette within a nephelometric optics module. A sensor senses the temperatures of reaction buffer liquids as they flow into the cuvette, and a heat exchanging device increases or decreases the temperatures of the buffer liquids. A control circuit responsive to the temperature sensor controls the heat exchanging device to maintain the temperature of the buffer liquids and the cuvette within a selected temperature range. The system may also include a sample pickup station, a sample probe for withdrawing a selected sample from the sample pickup station, a sample preparation station, and a sample transport for carrying said sample from the sample preparation station to the reaction cuvette. The system may include an antibody pickup station, an antibody probe for withdrawing an antibody from the antibody pickup station, an antibody preparation station, and an antibody transport for carrying the antibody from the antibody preparation station to the reaction cuvette.

Method of performing nephelometric analysis with independent temperature

Apparatus for sensing liquid levels in fluid transfer mechanisms and the like comprises a conductive member supporting containers for sample liquids, the conductive member being rotatably mounted for positioning selected containers under a conductive pipette probe. A low-frequency oscillator is capacitively coupled to the conductive member for generating an alternating electric field and producing an electrical signal at the probe. As the probe is lowered toward the liquid, an amplifier circuit monitors an electrical signal received by the probe. When the probe contacts the liquid, the amplifier detects a signal level in excess of a threshold level and produces an output signal for inhibiting the downward movement of the probe at the moment of contact with the liquid.

Liquid level sensor

A method for driving a stepper motor. The method includes varying the width of the high level drive impulses of a bi-level drive system based on the desired speed to be achieved by the stepper motor. A microprocessor is used to vary the pulse width.

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Fullerton, CA, United States of America

Peter Kan