Ribotargets Limited

Peter Jonathan Gasking Butler

Roger Kingdon Craig

Jonathan Karn

Alistair Simpson Irvine

Rodney Warren Zemmel

The invention relates to an isolated nucleic acid comprising two operatively linked binding sites for HIV Rev protein, the sites comprising a nucleation motif and an oligomerization motif, wherein the nucleic acid binds Rev protein monomers with a higher degree of cooperativity than wild-type RRE.

Methods and compositions for combating HIV infection

The invention relates to an isolated nucleic acid comprising two operatively linked binding sites for HIV Rev protein, the sites comprising a nucleation motif and an oligomerization motif, wherein the nucleic acid binds Rev protein monomers with a higher degree of co-operativity than wild-type RRE.

Growing community of inventors

Cambridge, United Kingdom

Peter Jonathan Gasking Butler