Sarnoff Corporation

David Sarnoff Research Center, Inc.

Intuity Medical, Inc.

Blue Marlin LLC

Rosedale Medical, Inc.

Delsys Pharmaceutical Corporation

Other

General Electric Company

Orchid Biosciences, Inc.

Peter John Zanzucchi

Satyam Choudary Cherukuri

Sterling Eduard McBride

Sterling Edward McBride

Richard Morgan Moroney, Iii

John Gregory Aceti

Christopher C Gregory

William Ronald Roach

Robert Richard Demers

Aaron W Levine

Peter David Southgate

Bawa Singh

Howard Christopher Rivenburg

Eugene Samuel Poliniak

Nitin Vithalbhai Desai

David A Keller

William Chiang

Dominic Stephen Rosati

Nalin Kumar

Charlotte A Burton

Lawrence Harrison Hammer

Paul J Stabile

Amrit K Judd

David Norman Ludington

Alexei Guennadievich Tsekoun

Arye Rosen

Barry Jay Thaler

Timothy Allen Pletcher

Robert L Quinn

Joseph H Abeles

Zvi Gerald Loewy

Steven A Lipp

Zygmunt Marian Andrevski

Pamela Kay York

Hoi Cheong Steve Sun

Zhonghui Hugh Fan

Jonathan Bernstein

Paul Heaney

Herschel Clement Burstyn

Paul Leonard Braun

Richard Morgan Moroney

Christopher Carter Gregory

James Harold Atherton

James Regis Matey

George L Schnable

Hoi Cheong Sun

Timothy James Davis

Suggy S Chrai

Rajan Kumar

Alan Michael Braun

Ramaswamy Murari

Frank Guarnieri

Ralph Doud Whaley, Jr

Bogdan Brycki

Aaron Wiliam Levine

Thomas Louis Fare

Israel Haim Kalish

Bryan Lloyd Bentz

John P Riganati

Judith Ann Ladd

Zhong Hui Fan

Russell Todd Granzow

Wen Ho

Helen Jiang Semus

Richard Moroney

Dominic Joseph Lo Iacono

Zvi Gerald Lowey

Zhong Hui Hugh Fan

Hoi Cheong (Steve) Sun

Prince Lal

Zhong H Fan

Sterling Eduard Mcbride

Sterling E Mcbride

Nitin V Desai

Bobby Varma

Richard Morgan Iii Moroney

Sterling Mcbride

Alexi Guennadievich Tsekoun

The invention relates to analyte monitoring/drug (pharmaceutical agent) delivery device. The invention is suited for monitoring various blood constituents such as glucose. The device has a housing that at least partially encloses a plurality of microneedles disposed on a carrier and an electronics portion. Each microneedle is in fluid communication with a corresponding microchannel. Each microneedle is individually addressable. That is, each microneedle can be extended and retracted individually via an actuator. The electronics portion includes a processor and associated circuitry (e.g., memory, supporting electronics and the like), a motor or the like, a sensor, a power supply (e.g., battery) and optionally an interface. In general, the processor controls the operation of the device and is data communication with the actuator, motor, sensor and interface. The invention provides for autonomous operation, that is, without intervention of the user. The invention can optionally provide for calibration without intervention of the user. The invention can also provide for semi-continuous monitoring for day and night time. The invention can provide for up to four, or more, weeks of operation. The invention can provide for a device that is relative small in size, and therefore unobtrusive. The invention can also provide for device with remote control and interactive electronics. The invention may be also used for the delivery of various pharmaceutical agents including high potency drugs to minimize patient intervention and minimize discomfort.

Autonomous, ambulatory analyte monitor or drug delivery device

The invention relates to analyte monitoring/drug delivery device. The invention is suited for monitoring various blood constituents such as glucose. The device has a housing that at least partially encloses a plurality of microneedles disposed on a carrier and an electronics portion. Each microneedle is in fluid communication with a corresponding microchannel. Each microneedle is individually addressable. That is, each microneedle can be extended and retracted individually via an actuator. The invention can optionally provide for calibration without intervention of the user and can also provide for semi-continuous monitoring for day and night time. The invention can provide up to four, or more, weeks of operation. The invention can provide for a device that is relatively small in size, and therefore unobtrusive. The invention can also provide for device with remote control and interactive electronics. The invention may be also used for the delivery of various pharmaceutical agents.

Arrangements for the detection of the presence and/or concentration of an analyte in a sample of bodily fluid include diffuse transmission, diffuse reflection and edge or waveguide illumination arrangements. A vertical flow assay arrangement and/or technique is also disclosed, and includes a detection component that can be in the form of an array of optical detection elements. A number of assay pad constructions are described which may include at least one or more of the following components: a prefilter component, a reflective component, a membrane component, a reagent component, a mesh component, and a component to prevent lateral spreading.

Analyte concentration detection devices and methods

A device detects the location of patterned objects in an environment by receiving an optical image and converting the optical image of the lost object into a color digital image. The device employs software to perform an analysis of the color digital image to detect the location of the one or more patterned objects in the environment by using color characteristics of light reflected from a pattern on the one or more patterned objects. The software uses a range of the visible portion of the color space uniquely identified for the light reflected from the pattern on the object and identifies those pixels in the digital image that may be possible targets.

Reflection spectroscopic means for detecting patterned objects

Provided is an analyte monitoring device having a housing, the device comprising: a plurality of needles, each having a tip, a retracted position, a position wherein the tip is extended from the housing a distance adapted to pierce skin; an electrically or spring powered needle pushing apparatus movable to separately engage each of the needles to move each from the retracted position to the extended position; an energy source located within the housing; a plurality of analysis sites comprising an analysis preparation, each adapted to receive liquid from the needles to wet the analysis preparation; one or more light sources adapted to direct light at the analysis sites; one or more light detectors adapted to receive light from the analysis sites; and a processor.

Analyte monitor

A cell suitable for use with an atomic clock and a method for making the same, the cell including: a silicon wafer having a recess formed therein; at least one amorphous silicate member having an ion mobility and temperature expansion coefficient approximately that of silicon sealing the recess; and, an alkali metal containing component and buffer gas contained in the recess. The method includes: providing a silicon wafer; forming a cavity through the silicon wafer; introducing an alkali metal containing component and buffer gas into the cavity; and, anodically bonding at least one amorphous silicate member having an ion mobility and temperature expansion coefficient approximately that of silicon to the wafer to close the cavity.

Anodically bonded cell, method for making same and systems incorporating same

Imaging circuitry integrated into a golf club head, such as a putter, obtains an image from as the golf club head strikes a golf ball as well as successive images after the golf ball is struck, such n&#x3c;5. The images can be analyzed by integral computational software provided in the imaging device operable to (i) analyze whether the ball was struck in the middle of the golf club head, (ii) whether the golf club head was square to the target and (iii) based on comparison of n successive images, calculate the immediate path of the golf ball.

Method and imager for determining the point of impact on a putter face

A one dimensional (1D) line imaging system that operates at a scanning (clock) rate of between 10-40 MHz is used to monitor the characteristics of a golf swing. A line image is analyzed in real time by an associate computer imaging system removing the need for a trigger to operate. Optics of the imaging system are designed to relate ball image size to distance so that the number of 1 D pixels imaging the ball, in particular sensing a white object, have a relation to distance to the ball. Ball image size is related to distance by monitoring the rate of increase (rate of change) of the pixels imaging the ball with time so that the speed of the club head can be determined. The speed of a golf ball that has been struck is determined by monitoring the rate of decrease (rate of change) of the pixels imaging the ball.

Method and system for determining club head speed

A device detects the location of objects in an environment by receiving an optical image and converting the optical image of the lost object into a color digital image. The device employs software to perform an analysis of the color digital image to detect the location of the one or more objects in the environment by using color and shape characteristics of the one or more objects. The software uses a range of the visible portion of the color space uniquely identified for the type of object in that environment and identifies those pixels in the color digital image that may be possible targets. Intensity of background and object size are used to exclude pixels as possible target objects.

Method and imager for detecting the location of objects

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Princeton Junction, NJ, United States of America

Peter John Zanzucchi