Pfizer Corporation

Phaeton Research Limited

Minnesota Mining and Manufacturing Company

R.p. Scherer Corporation

Pharmacia Aktiebolag

Scottish & Newcastle Limited

Peter John Houzego

John Kelshaw Conway

Andrew Mark Bryant

Martin Douglas Pearl

Peter Neil Morgan

Ian Wilding

Duncan James Westland

Peter Hanson Hirst

Howard Norman Stevens

Jonathan Kenneth Embleton

Sarah A Rocca

Richard J Malcolmson

Stephen P Jones

Luigi G Martini

Peter D Hodson

Timothy Michael Wood

Eric A Baum

Andrew John Ede

Paul A Robertson

Borge R Jensen

Peter Erich Cox

Murray A Creeke

Neil Emerton

John Martin Hewett

Stuart Justin Nash

A device for dispensing individual doses of powder from respective pockets of a disc-shaped carrier by outwardly rupturing a lidding foil by means of pressure on an opposite side surface, the device providing individual respective deaggregation flow paths for each pocket, split airstreams allowing improved entrainment of powder, a cam mechanism for outwardly rupturing the pockets, an indexing mechanism linked to the cam mechanism and a dose counter.

Dispensing device

A method and apparatus for filling with powder () a container () having an open end, including positioning an outlet of a hopper () containing powder above the open end of the container (), mechanically agitating the hopper so as to cause powder () to be transferred from the hopper to the container and mechanically agitating the container, wherein the steps of mechanically agitating are conducted by at least a predetermined amount sufficient to ensure that the container is filled with powder at a predetermined density.

Method and apparatus for filling a container

An ingestible device for delivering a substance to a chosen location in the GI tract of a mammal includes a receiver of electromagnetic radiation for powering an openable part of the device to an opened position for dispensing of the substance. The receiver includes a coiled wire that couples the energy field, the wire having an air or ferrite core. In a further embodiment the invention includes an apparatus for generating the electromagnetic radiation, the apparatus including one or more pairs of field coils supported in a housing. The device optionally includes a latch defined by a heating resistor and a fusible restraint. The device may also include a flexible member that may serve one or both the functions of activating a transmitter circuit to indicate dispensing of the substance; and restraining of a piston used for expelling the substance.

Ingestible device

A method and apparatus for introducing powder into a pocket () using a dosator () having an elongate cavity with an open end and a plunger () opposite the open end moveable along the cavity so as to define, between the plunger () and the open end, a space of variable volume, the method including, with the plunger () defining a volume greater than that of the pocket (), inserting the open end into a source of powder so as to fill the volume with powder, positioning the open end over the pocket, driving the plunger so as to expel powder from the open end into the pocket and compress it to a predetermined bulk density and removing the open end from the pocket so as to leave the pocket full of powder with the predetermined bulk density.

Method and apparatus for introducing powder into a pocket

The field of the invention is site-specific drug delivery capsules (SSDC's). The disclosure relates to a closure member () for a substance reservoir () of an SSDC (). The SSDC () includes a retainer that provides a non-linear force resisting opening of the closure member (). The non-linear force ensures that the closure member () unseals the reservoir () only when an opening force exceeds a maximal value of the resisting force, thereby preventing premature or accidental emptying of the reservoir (). The preferred means of providing the resistive force is a rolling, elastomeric o-ring () that additionally seals the closure member () into an aperture ().

Ingestible device for the release of substances at distinct locations in alimentary canal

A unit container for a treatment fluid comprises a sealed enclosure of which one wall section thereof is formed with at least one opening. The enclosure is pressuriseable to discharge its contents through the opening or openings, which is or are of sufficient diameter to enable the generation of a jet and/or discrete droplets of treatment fluid discharged therefrom. The one wall section is typically a flat section of the enclosure wall, and the enclosure is typically a blister pack, with the wall section at a planar base of the blister. However, the one wall section may be dome-shaped and formed with at least one opening in the top region of the dome. Containers of the invention may be provided in packages, for example in strip form or in planar arrays. Dispensing devices are described for discharging their contents in treatment.

Ocular treatment device

Beverage enhancer

Growing community of inventors

Cambridge, United Kingdom

Peter John Houzego