Versi Group, LLC

Mount Cook Bio Sciences, Inc.

Ardent Pharmaceuticals, Inc.

Peter J Gengo

William Pendergast

Kwen-Jen Chang

Xin Ma

Kestutis P Biciunas

Shyi-Tai Jan

Compositions and methods for treatment of a urinary tract dysfunction by administering to a subject in need of such treatment a pharmaceutical composition including a delta opioid receptor agonist in an amount effective to reduce the effects of the urinary tract dysfunction. The compositions may further include an additional active agent that is used to treat urinary tract dysfunctions, e.g., alpha-adrenergic agonists, anticholinergics, alpha-adrenergic antagonists and tricyclic antidepressants.

Compositions and methods for combating lower urinary tract dysfunctions with delta opioid receptor agonists

The present invention relates to compositions and methods of treatment for cardioprotection through the use of non-peptidic delta opioid receptor agonist compound(s) that mediate cardioprotective effects of ischemic preconditioning. The compounds are used to reduce injury associated with ischemia and reperfusion of cardiac tissue. Further, the compounds may be used in solutions preserving the viability of an isolated organ.

Cardioprotective delta opioid receptor agonists and methods of using same

Methods for treatment of depression or other affective mood disorders, such as bipolar manic depression or seasonal affective disorder, are disclosed by administration to a subject suffering or susceptible to same, of therapeutically effective diarylpiperazine compounds as herein described.

Method of treating depression with delta receptor agonist compounds

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Raleigh, NC, United States of America

Peter J Gengo