Catharos Medical Systems, Inc.

Apica Cardiovascular Limited

Flea Street Translational, LLC

St. Jude Medical, Cardiology Division, Inc.

Peter J Fitzgerald

Ali Hassan

Brian Courtney

Jorge Jimenez

James L Greene

Richard Cartledge

Lester John Lloyd

Leonard Y Lee

Nicolas A F Chronos

Brian K Courtney

Michael Orth

Mark Yang

Binh Luong

Embodiments of the invention provide systems, apparatus, device and methods for sealing a puncture in a tissue wall. According to one aspect, the system includes at least one supporting element for insertion into or placement on at least a portion of a tissue wall proximate a puncture to prevent expansion of the puncture; and a closing element adapted for at least partial insertion into the tissue wall and shaped to compress at least a portion of a tissue wall in an inward direction to close the tissue puncture when inserted at least partially into the tissue wall.

Systems for sealing a tissue wall puncture

Methods, systems and devices for effectively and safely accessing and verifying a target site within a vessel or body cavity undergoing a catheter-based procedure or treatment. The present invention further includes the accurate delivery an instrument, an implantable device and/or materials to the target site. The present invention is particularly useful for transvenously assessing the suitability of a target site within the coronary vasculature for placement of a pacing electrode and transvenously placing the pacing electrode at the target site.

Sensor-assisted catheter-based procedures

Methods and devices for modulating heart valve function are provided. In the subject methods, a heart valve is first in structurally modified. Blood flow through the structurally modified heart valve is then monitored, and the heart is paced in response to the monitored blood flow. Also provided are devices, systems and kits that find use in practicing the subject methods. The subject methods find use in a variety of applications.

Methods and devices for modulation of heart valve function

Methods and devices for selectively removing an agent from a physiological site, e.g., a physiological efferent fluid collection site, are provided. Aspects of the invention include fluid removal (e.g., aspiration) devices having a fluid removal element and a flow modulator positioned at a distal end of the fluid removal element. The flow modulator is configured to converge intersecting fluid flow paths into the fluid removal element. Also provided are systems and kits for performing the subject methods. The subject invention finds use in a variety of different applications, including the selective removal of both therapeutic and diagnostic agents from a variety of different physiological sites.

Methods and devices for removal of a medical agent from a physiological efferent fluid collection site

Methods, systems and devices for establishing communication between organs and/or tissue lumens. The devices include catheters having magnetized distal ends which are configured to magnetically couple to each other such that a coaxial alignment is established between two or more catheters. The systems include two or more the subject catheters. The methods include use of the catheters and magnetically coupling them to establish a continuous passageway between them.

Methods, systems and devices for establising communication between hollow organs and tissue lumens

Methods and devices for selectively removing an agent from a physiological efferent fluid collection site are provided. A feature of the invention is that a non-occlusive aspiration device is employed to selectively remove the target agent from the site only when the target agent is present in the site. Also provided are systems and kits for performing the subject methods. The subject invention finds use in a variety of different applications, including the selective removal of both therapeutic and diagnostic agents from a variety of different physiological sites.

Growing community of inventors

Portola Valley, CA, United States of America

Peter J Fitzgerald