Proxy Biomedical Limited

Viscus Biologics, LLC

The Cleveland Clinic Foundation

Peter Hayes Gingras

Gabriela Voskerician

Michael F White

Justin Jeffrey Baker

Joseph P Iannotti

Dean King

Sambit Sahoo

Tony Durkin

Cormac Breathnach

Niall Rooney

Robert Priest

Andrew Ryan Baker

Kathe Derwin

A fiber-based radiopaque tissue marker for radiographic marking of tissue is provided. The marker is a sterile, single-patient-use polymeric fiber with a radiopaque material and a dye. The marker is radiopaque using standard radiographs such as x-rays and mammography. The marker can also be visualized by low-dose CT scans.

Radiopaque tissue marker

A method of treating or preventing a microbial infection in a subject is described. The method includes contacting a microorganism within the subject with a composition comprising one or more species of amoebae of the genus. Antibiotic wound dressings and kits for providing amoeba for treatment or prevention of microbial infection in a subject are also described.

Amoeba therapeutic dressings, biomaterials, and solutions

The present invention is concerned with a method of manufacturing a tissue-integration device, and a tissue-integration device so produced, the method comprising the steps of wrapping a porous sheet of material around a mandrel in order to create overlapping layers of the porous sheet material, the wrapped mandrel then being placed in a mould in order to apply pressure and heat to the overlapping layers in order to effect the lamination thereof such as to form a device having spaces defined by overlapping pores of the adjacent layers.

Method of providing interconnected pores with a growth-promoting medium for controlled tissue integration

A gastric constriction device comprises a sheet extending over part of the wall of the stomach. Five bands extend around the stomach to fix the sheet in position relative to the stomach. The lower two bands extend from the first side of the sheet around the stomach only partially towards the second side. These lower two bands are not fixed to the second side. This arrangement results in an unconstricted portion of the stomach. In this manner, the device restricts expansion of the majority of the stomach wall while facilitating expansion of this unconstricted portion. The unconstricted portion is therefore free to expand or bulge outwardly upon ingestion. This expansion may trigger the feeling of satiation due to the presence of the vagal nerves in this portion of the stomach.

Gastric constriction device

Described herein are tissue repair implants comprising at least a first layer of peritoneal membrane. The first layer of peritoneal membrane can be located adjacent to a second layer of peritoneal membrane and can be in direct contact with the second layer of peritoneal membrane. Additional layers (e.g., a third or fourth layer) can be included. Where more than one layer is present, the layers can be affixed to one another. For example, a first layer of peritoneal membrane can be attached to the second layer of peritoneal membrane by an adhesive bond, suture, or staple. One or more of the peritoneal membranes can be non-crosslinked, partially crosslinked, or substantially fully crosslinked. Any of the layers of peritoneal membrane may be attached to a wall (e.g., an interior or exterior wall) of an abdominal tissue by an adhesive, suture, and/or staples.

Tissue repair implant

A tissue scaffold includes a first film having a plurality of cell openings and a second film adjacent the first film and having a plurality of cell openings larger than the cell openings of the first film. The cell openings of the first film interconnect with the cell openings of the second film to define pathways extending through the first and second films.

Tissue scaffold

The present invention features soft tissue implants and methods for making same. The implants can includes a biocompatible film that is rendered porous due to the inclusion of uniformly or non-uniformly patterned cells, and the film has a thickness of less than about 0.015 inches in the event the starting material is non-porous and less than about 0.035 inches in the event the starting material is a microporous film. Multi-film implants can also be made.

Soft tissue implants and methods for making same

The present invention features soft tissue implants comprising major and minor struts and methods for making same. The implants can includes a biocompatible film that is rendered porous due to the inclusion of uniformly or non-uniformly patterned cells, and the film has a thickness of less than about 0.015 inches in the event the starting material is non-porous and less than about 0.035 inches in the event the starting material is a microporous film. Multi-film implants can also be made.

Growing community of inventors

Shaker Heights, OH, United States of America

Peter Hayes Gingras