Bayer Pharma Aktiengesellschaft

Bayer Aktiengesellschaft

Schering Aktiengesellschaft

Schering Aktiengesellchaft

Peter Hauff

Ulf Bömer

Ulrich Bothe

Judith Günther

Martin Lange

Holger Siebeneicher

Christian Stegmann

Reinhard Nubbemeyer

Holger Steuber

Alexandra Rausch

Nicole Schmidt

Andreas Sutter

Christian Friedrich

Raimund Kast

Hartmut Beck

Jens Nagel

Chantal Fuerstner

Thomas Fritzsch

Lisa Dietz

Dieter Heldmann

Timo Stellfeld

Mark Meininghaus

Werner Weitschies

Joerg Mueller

Michaela Bairlein

Harald Stahl

Clemens-Jeremias Von Buehler

Sonja Anlauf

Carsten Terjung

Karoline Droebner

Hannah Joerissen

Johanna Anlahr

Uwe Muenster

Michael Reinhardt

Andreas Briel

The present application relates to novel substituted indazoles, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of endometriosis and endometriosis-associated pain and other endometriosis-associated symptoms such as dysmenorrhoea, dyspareunia, dysuria and dyschezia, of lymphoma, rheumatoid arthritis, spondyloarthritis (especially psoriatic spondyloarthritis and Bekhterev's disease), lupus erythematosus, multiple sclerosis, macular degeneration, COPD, gout, fatty liver disorders, insulin resistance, neoplastic disorders and psoriasis.

Substituted indazoles, methods for the production thereof, pharmaceutical preparations that contain said substituted indazoles, and use of said substituted indazoles to produce drugs

The present application relates to novel substituted N-arylethyl-2-aminoquinoline-4-carboxamide derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of fibrotic and inflammatory disorders.

Substituted N-arylethyl-2-aminoquinoline-4-carboxamides and use thereof

The present application relates to novel substituted N-arylethyl-2-arylquinoline-4-carboxamide derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of fibrotic and inflammatory disorders.

Substituted-arylethyl-2-arylquinoline-4-carboxamides and use thereof

Substituted indazoles, methods for the production thereof, pharmaceutical preparations that contain said new substituted indazoles, and use of said new substituted indazoles to produce drugs

In the quantification of bodies, especially bubbles, in ultrasonic diagnosis, the problem exists that the concentration of bodies, especially bubbles, is often so high that the image data that is obtained relative to the visualization becomes saturated, such that a quantification is impossible. To solve this problem, it is proposed that the bodies that are contained in the sectional layers of an object under examination first be excited by means of ultrasound to produce characteristic signals and to pick up these signals, to form data sets from the signals, to convert the data sets into an image of the body arrangement in the object under examination and to determine the number of bodies therefrom, whereby at least two ultrasonic signal sets from overlapping sectional layers in the object under examination are picked up.

Device and process for quantifying bodies by means of ultrasound

The invention relates to new microparticles containing active ingredients, which contain at least one gas or a gaseous phase in addition to the active ingredient(s), agents containing these particles (microparticulate systems), their use for ultrasound-controlled in vivo release of active ingredients, as well as a process for the production of particles and agents.

Microparticles containing active ingredients, agents containing these microparticles, their use for ultrasound-controlled release of active ingredients, as well as a process for their production

Microparticles containing active ingredients, agents containing these

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Berlin, Germany

Peter Hauff