Lonza Inc.

Lonza Ag

Peter Hardt

Ulrich Daum

Pavel Lehky

Theodor Volker

Pius Abgottspon

Andrej Stravs

4,4'-methylene-bis-(3-chloro-2,6-dialkylphenylisocyanates)

A process for the production of 4,4'-(phenylenediisopropyl)bis(2,6-dialkylanilines) of the general formula: ##STR1## wherein R.sub.1 and R.sub.2 are the same or different and each is a (C.sub.1 -C.sub.4)alkyl group, R.sub.3 is hydrogen or halogen, and the central phenylene function is substituted in the 1,3 or 1,4 position, by reaction of a corresponding diisopropyl benzene with a corresponding aniline in the presence of catalytic amounts of aluminum chloride. The 4,4'-(phenylenediisopropyl)-bis(2,6-dialkylanilines) are used as cross-linking agents for epoxy resins, as chain lengthening agents for polyurethanes, for the production of hydrolysis protective agents for polyurethanes, or for the production of UV stabilizers in varnishes.

Process for the production of 4, 4'-(phenylene-diisopropyl)-bis(2,

Process, which is feasible on a commercial scale, for the production of gamma-butyrobetaine. For this purpose, butyrolactone with hydrogen chloride and an alcohol is converted to the chlorobutyric acid ester, the trimethylammonium butyric acid salt is formed with trimethylamine and then saponified to the end product.

Process for the production of gamma-butyrobetaine

Process for the production of 7-ethyl indole by dehydrocyclization of 2,6-diethylaniline and then partial hydrogenation of the accumulated raw product.

Process for the production of 7-ethyl indole

Process for the production of 3,3-dimethylglutaric acid from isophorone. In a first step the isophorone is converted with ozone into an ozone-addition product. The ozone-addition product is converted by hydrolysis into 3,3-dimethyl-5-oxohexanoic acid. The latter is converted into 3,3-dimethylglutaric acid by treatment with hydrogen peroxide.

Process for the production of 3,3-dimethylglutaric

A process for the catalytic production of a 2-substituted pyridine which comprises reacting a corresponding cyano compound and acetylene in the presence of cobaltocene. A favorable conversion speed, a conversion of at least 90 percent, a good yield and a high selectivity are obtained.

Process for the catalytic production of 2-substituted pyridines

A process for the catalytic production of a 2-substituted pyridine which comprises reacting a corresponding cyano compound and acetylene in the presence of cobaltocene. Favorable conversion speed, conversion of at least 90 percent, good yield and high selectivity are obtained.

A process for the production of 2-vinyl pyridine from a 2-(.beta.-substituted ethyl)-pyridine involves using, as the starting material, a 2-(.beta.-aminoethyl)-pyridine having the formula set out below. The 2-(.beta.-aminoethyl)-pyridine is split by the action of a carrier-bound alkali hydroxide, as a catalyst, at a temperature between 100.degree. and 500.degree. C. into 2-vinyl pyridine and the corresponding secondary amine. The 2-(.beta.-aminoethyl)-pyridine has the formula: ##STR1## wherein R.sub.1 is the same as or different from R.sub.2, and R.sub.1 and R.sub.2 each are alkyl having one to eight carbon atoms, cycloalkyl, wherein the alkyl moiety has three to eight carbon atoms, or aralkyl, wherein the alkyl moiety has one to eight carbon atoms, or R.sub.1 and R.sub.2 together are --(CH.sub.2).sub.n -- wherein n is 4 or 5 or R.sub.1 and R.sub.2 together are --(CH.sub.2).sub.2 --O --(CH.sub.2).sub.2.

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Visp, Switzerland

Peter Hardt