Phaeton Research Limited

Peter Hanson Hirst

Peter John Houzego

Peter Neil Morgan

Ian Wilding

Duncan James Westland

Ian Robert Wilding

An ingestible device for delivering a substance to a chosen location in the GI tract of a mammal includes a receiver of electromagnetic radiation for powering an openable part of the device to an opened position for dispensing of the substance. The receiver includes a coiled wire that couples the energy field, the wire having an air or ferrite core. In a further embodiment the invention includes an apparatus for generating the electromagnetic radiation, the apparatus including one or more pairs of field coils supported in a housing. The device optionally includes a latch defined by a heating resistor and a fusible restraint. The device may also include a flexible member that may serve one or both the functions of activating a transmitter circuit to indicate dispensing of the substance; and restraining of a piston used for expelling the substance.

Ingestible device

The field of the invention is site-specific drug delivery capsules (SSDC's). The disclosure relates to a closure member () for a substance reservoir () of an SSDC (). The SSDC () includes a retainer that provides a non-linear force resisting opening of the closure member (). The non-linear force ensures that the closure member () unseals the reservoir () only when an opening force exceeds a maximal value of the resisting force, thereby preventing premature or accidental emptying of the reservoir (). The preferred means of providing the resistive force is a rolling, elastomeric o-ring () that additionally seals the closure member () into an aperture ().

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Nottinghamshire, United Kingdom

Peter Hanson Hirst