Siemens Medical Solutions Usa, Inc.

University of Illinois

Pronova Solutions, LLC

Other

Siemens Aktiengesellschaft

The Procter Gamble Company

Interactive Pictures Corporation

Ipix Corporation

Peter Hansen

Vladimir Gartstein

Dragan Danilo Nebrigic

Nicholas Busko

Milan Marcel Jevtitch

James Vig Sherrill

Michael E Casey

William Thomas Milam

James Luke Corbeil

Nan Zhang

H Lee Martin

Stefan B Siegel

Mehmet Aykac

Joseph C Matteo

Jonathan Huber

Robert A Mintzer

Johannes Breuer

Sanghee Cho

Martin L Bauer

Alexis S Pecoraro

James Christopher Arnott

Laban Phelps Jackson

Maciej P Kapusta

William Thomas Mllam

Debora Henseler

Meinrad Schienle

Stephan Siegel

A scintillation block detector employs an array of optically air coupled scintillation pixels, the array being wrapped in reflector material and optically coupled to an array of silicon photomultiplier light sensors with common-cathode signal timing pickoff and individual anode signal position and energy determination. The design features afford an optimized combination of photopeak energy event sensitivity and timing, while reducing electronic circuit complexity and power requirements, and easing necessary fabrication methods. Four of these small blocks, or 'miniblocks,' can be combined as optically and electrically separated quadrants of a larger single detector in order to recover detection efficiency that would otherwise be lost due to scattering between them. Events are validated for total energy by summing the contributions from the four quadrants, while the trigger is generated from either the timing signal of the quadrant with the highest energy deposition, the first timing signal derived from the four quadrant time-pickoff signals, or a statistically optimum combination of the individual quadrant event times, so as to maintain good timing for scatter events. This further reduces the number of electronic channels required per unit detector area while avoiding the timing degradation characteristic of excessively large SiPM arrays.

Silicon photomultiplier based TOF-PET detector

Apparatuses and methods are provided that minimize the effects of dark-current pulses. For example, in one embodiment of the invention, a method is provided where a first pixel is struck (i.e., a primary pixel). Pixels struck within a fixed time frame after the primary pixel is struck are referred to as secondary pixels. After a short fixed time frame has expired, the number of primary and secondary pixels is added. If the count exceeds a threshold, the primary pixel was activated by the first (or early) photon from a true gamma event. If the threshold is not met then it is likely the primary pixel generated a dark pulse that should be ignored.

Integrated digital discriminator for a silicon photomultiplier

A gantry wheel adjustment system and method to adjust a gantry wheel of a proton treatment system, including an estimation unit to estimate a bearing adjustment value for each of the adjustable bearings based on a stiffness parameter of each adjustable bearing, the stiffness parameter being a function of a force applied at each adjustable bearing and a deflection of the gantry wheel associated with the force applied at each adjustable bearing, the bearing adjustment value corresponding to a nominal position value for each adjustable bearing to compensate for gantry wheel flexing when the gantry wheel is rotated from a first angular position to a second angular position, the adjustable bearings being configured to support the gantry wheel on the bearing surface and maintain the proton beam at the isocenter of the gantry wheel during gantry wheel rotation.

Systems and methods of adjusting a rotating gantry system

Single and multiple cell batteries are provided with built-in controllers that monitor the cell or cells and provide a safety disconnect when certain monitored conditions are detected by the controller. Preferred single and multiple cell batteries have their cell or cells within a container having a positive terminal and a negative terminal. The built-in controller monitors the cell or cells for each of the following conditions: over temperature, short-circuit, overcharge, and over-discharge and the controller provides a safety disconnect when one of the monitored conditions exist. A multiple cell battery includes a built-in controller that monitors the temperature of the cells and provides a safety disconnect that electronically disconnects all of the cells when at least one of the cells exceeds a predetermined temperature, or a controller that monitors the state of charge of each of the cells and individually controls the charge cycle of each of the cells, or a controller that monitors the temperature of the cells and to provides a safety disconnect when at least one of the cells exceeds a predetermined temperature.

Single and multiple cell battery with built-in controller

Systems and methods of generating timing triggers to determine timing resolutions of gamma events for nuclear imaging includes receiving a pulse signature representing a succession of triggers associated with a photomultiplier. When a number of triggers occurring within a predetermined time interval matches a predetermined number, an event trigger can be initiated. A delayed version of the pulse signature can be generated and compared to a predetermined timing trigger level. When the delayed version matches the predetermined timing trigger level, a timing trigger can be generated. Based on the timing trigger level, the timing trigger can be generated at the pulse of the delayed version that corresponds to the first photoelectron of a gamma event. The timing trigger can correspond to a timestamp for the first photoelectron so that a data acquisition system can identify the pulse from which to acquire energy information to generate a nuclear image.

System and method of determining timing triggers for detecting gamma events for nuclear imaging

A gantry apparatus for a proton treatment system, including a proton beam nozzle to emit a proton beam to a targeted region of a patient, a gantry wheel to support the proton beam nozzle to direct the proton beam to an isocenter of the gantry wheel corresponding to a center of the targeted region, a plurality of adjustable bearings incrementally spaced apart along an outer diametrical surface of the gantry wheel, and a bearing surface to support a portion of the adjustable bearings such that when the wheel is rotated from a first angular position to a second angular position, at least a portion of the bearings contact the bearing surface to raise or lower the gantry wheel to realign the proton beam to the center of the targeted region.

Proton treatment gantry system

A power converter for coupling an energy source to a load device comprising a selectively coupled output stage to deliver energy from an energy source to a load device, a controller coupled to the output stage, an output stage, a capacitive element coupled to the output terminals, a rectifying element, and a switch responsive to a control signal from the controller. The rectifying element and switch are coupled to the inductive and capacitive elements. The controller is responsive to input signals for generating the control signal to open the switch in a first state and close the switch in a second state. The input signals to the controller produce one or more output voltages across the output terminals, an input voltage across the input terminals, a selectable reference voltage and a feedback signal measured with respect to the inductive element.

Oscillatorless DC-DC power converter

Apparatus for interactive display of any portion of a spherical image preferably comprises a personal computer or other digital processor apparatus for storing digital data representative of at least one image having a 180 degree or greater field of view (or hemispherical image). In order to view a selected image portion without warp or distortion at the seam between opposite hemispherical images, edge filtering is applied to eliminate a halo effect. Moreover, an opposite hemispherical image may either be obtained by creating a mirror image of a first hemispherical image or by capturing a second hemispherical image by means of an oppositely directed camera and storing the digital image. Equations for image transformation are based on a lens' characteristics including the lens' radius R. An input interface preferably comprises a display including a magnification region and a directional cursor for pointing the direction to a next spherical image. &ldquo;Hot spots&rdquo; can be linked to audio, text, graphics, or other media or trigger a charge for a pay event or identify program links to the next spherical image.

Method and apparatus for the interactive display of any portion of a spherical image

A charge pump power converter efficiently provides electrical power by dynamically controlling a switch matrix of the charge pump. Instead of open-loop oscillator-based control, a dynamic controller provides power upon demand by sensing the output voltage and changing the operating frequency of the charge pump in response. Moreover, this closed-loop dynamic control intrinsically voltage regulates the output voltage of the charge pump power converter without the inefficient addition of a step-down voltage regulator, downstream of the power converter. Additional efficiencies are achieved through maintaining the voltage ripple across the fly capacitor and/or the load capacitor. Also, a three-state control scheme is used to charge the fly capacitor, wait for the output voltage to drop to a predetermined level, and discharge the fly capacitor. Furthermore, a multiple-output charge pump power converter provides multiple voltage levels for devices such as portable communication electronic devices.

Multiple output dynamically regulated charge pump power converter

A charge pump power converter efficiently provides electrical power by dynamically controlling a switch matrix of the charge pump that includes a flying ultra-capacitor C . Instead of open-loop oscillator-based control, a dynamic controller provides power upon demand by sensing the output voltage and changing the operating frequency of the charge pump in response. Moreover, this closed-loop dynamic control intrinsically voltage regulates the output voltage of the charge pump power converter without the inefficient addition of a step-down voltage regulator, downstream of the power converter. In addition, this closed-loop dynamic control allows for maintaining a desired output voltage even with variations in the input voltage. Further efficiency is achieved by controlling the charging and discharging of the flying ultra-capacitor C , both in rate of current change and in voltage ripple.

Ultra-capacitor based dynamically regulated charge pump power converter

A charge pump power converter efficiently provides electrical power by dynamically controlling a switch matrix of the charge pump. Instead of open-loop oscillator-based control, a dynamic controller provides power upon demand by sensing the output voltage and changing the operating frequency of the charge pump in response. Moreover, this closed-loop dynamic control intrinsically voltage regulates the output voltage of the charge pump power converter without the inefficient addition of a step-down voltage regulator, downstream of the power converter. In addition, this closed-loop dynamic control allows for maintaining a desired output voltage even with variations in the input voltage. Also, the dynamic control accommodates the advantages of using ultra-capacitors in the charge pump. The power converter is capable of operating with a sub-one volt input voltage incorporating low-threshold, low on-resistance power MOSFET switches in the switch matrix of the charge pump. A progressive start-up circuit further allows the power converter to start from a discharged state even with a sub-one volt input voltage.

Dynamically-controlled, intrinsically regulated charge pump power converter

Apparatus for interactive display of any portion of a spherical image preferably comprises a personal computer or other digital processor apparatus for storing digital data representative of at least one image having a 180 degree or greater field of view (or hemispherical image). In order to view a selected image portion without warp or distortion at the seam between opposite hemispherical images, edge filtering is applied to eliminate a halo effect. Moreover, an opposite hemispherical image may either be obtained by creating a mirror image of a first hemispherical image or by capturing a second hemispherical image by means of an oppositely directed camera and storing the digital image. Equations for image transformation are based on a lens' characteristics including the lens' radius R. An input interface preferably comprises a display including a magnification region and a directional cursor for pointing the direction to a next spherical image. 'Hot spots' can be linked to audio, text, graphics, or other media or trigger a charge for a pay event or identify program links to the next spherical image.

Growing community of inventors

Knoxville, TN, United States of America

Peter Hansen