American Cyanamid Company

Peter Gautschi-Sova

Peter Bohlen

A group of growth factors, designated heparin-binding brain mitogens (HBBMs), is disclosed. The HBBMs are isolated from brain tissue by a sequence of purification steps. The growth factors may be useful in the promotion of angiogenesis, such as in the promotion of wound healing, bone healing and in the treatment of burns, as well as in promoting the formation, maintenance and repair of tissue, in particular, neural tissue.

Therapeutic compositions and methods for use of heparin-binding brain

Methods for the isolation of heparin-binding brain mitogens

A group of growth factors, designated heparin-binding brain mitogens (HBBMs), is disclosed. The HBBMs are isolated from brain tissue by a sequence of purification steps.

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Mellingen, Switzerland

Peter Gautschi-Sova