Ab Astra

Astra Aktiebolag

Aktiebolaget Astra

Kabi Pharmacia Ab

Peter Edman

Ann Charlotte Johansson

Kjell Goran Backstrom

Carl Magnus Dahlback

Ralph Lennart Brattsand

Stinabritt Nilsson

Bror Arne Thalen

Thomas Hogberg

Jan Erik Ulmius

Wideholt Bengt

Kristensen Arne

A therapeutic preparation for inhalation which comprises insulin and a substance which enhances the absorption of insulin in the lower respiratory tract, is provided in the form of a powder preparation suitable for inhalation.

Therapeutic preparation for inhalation

Novel compounds which are a glucocorticosteroid (GCS) chemically bound to a sugar, having the general formula

Colon or ileum-specific glucocorticosteroid derivatives

A pharmaceutical composition including a mixture of active compounds (A) a pharmaceutically active polypeptide, and (B) an enhancer compound which enhances the systemic absorption of the polypeptide in the lower respiratory tract of a patient, the mixture being in the form of a dry powder for inhalation in which at least 50% of the total mass of the active compounds consists of primary particles having a diameter less than or equal to about 10 microns, the primary particles optionally being formed into agglomerates.

Processes for preparing compositions for inhalation

Colon or ileum-specific steroid derivatives

A method of treating a patient in need of insulin treatment, including the steps of introducing into the lower respiratory tract of the patient an effective amount of a therapeutic preparation in the form of a dry powder containing (a) insulin and (b) an enhancer compound which enhances the absorption of insulin in the lungs of the patient.

Systemic administration of a therapeutic preparation

Therapeutical composition and process for its preparation

Growing community of inventors

Bjarred, Sweden

Peter Edman