Hoechst Aktiengesellschaft

Max-planck-gesellschaft Zur F&#xf6;rderung Der Wissenschaften E. V.

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Hoechst Schering Agrevo Gmbh

Peter Eckes

Jurgen Logemann

Jeff Schell

Guido Jach

John Mundy

Eugen Uhlmann

Burkhard Sachse

Joachim Wink

Peter Braun

Gunter Donn

Ilan Chet

Heinz Hanel

Denes Dudits

Jozef Schell

Katalin Paulovics

Rolf Hilgenfeld

Norbert Ulbrich

Hubert Mullner

Rudolf Schneider

Gabor Horvath

Katalin Kalman

Birgit Gornhardt

Bernadus Uijtewaal

Laszlo Bako

Ferenc Nagy

Janos Gyorgyey

Alfred Puhler

Wolfgang Wohlleben

Walter Arnold

Eckhard Strauch

Renate Alijah

Günter Donn

Attila Feher

Friedrich Wengenmayer

J&uuml;rgen Logemann

Hubert Müllner

Birgit Görnhardt

Jürgen Logemann

Friedrich Hein

Birgit G&ouml;rnhardt

Transgenic pathogen-resistant organism whose genome contains at least two different genes under the control of active promoters with pathogen-inhibiting action. This organism is distinguished by a synergistic pathogen-inhibiting action. This action is evident particularly when the genes code for the gene products chitinase (ChiS, ChiG), glucanase (GluG), protein synthesis inhibitor (PSI) and antifungal protein (AFP).

Transgenic pathogen-resistant organism

The invention is drawn to plant cell transformation with a nucleic acid construct comprising a prokaryotic ammonium-specific asparagine synthetase, type A, coding sequence, operably linked to a chloroplast transit peptide-encoding sequence, wherein said plant cells also contain a nucleic acid construct comprising a chloroplastic glutamine synthetase coding sequence in antisense orientation. Plant cells containing both nucleic acid constructs, and plants regenerated therefrom, exhibit improved growth characteristics.

Process for the production of plants with enhanced growth characteristics

Transgenic pathogen-resistant organism whose genome contains at least two different genes under the control of active promoters with pathogen-inhibiting action. This organism is distinguished by a synergistic pathogen-inhibiting action. This action is evident particularly when the genes code for the gene products chitinese (ChiS, ChiG), glucanase (GluG), protein synthesis inhibitor (PSI) and antifungal protein (AFR).

Transgenic pathogen-resistant plant

A multifunctional RNA having self-processing activity, the preparation thereof and the use thereof Host cells can be transformed so that they express ribozyme RNA and antisense RNA which are connected with each other via a spacer. The RNA molecules can, for example, be complementary to a certain viral RNA. Plants which have been transformed with genes coding for RNA of this type show a significantly improved resistance to viruses.

Multifunctional RNA having self-processing activity, the preparation

The polypeptide with the sequence (SEQ ID NO:1) Ala-Thr-Tyr-Asn-Gly-Lys-Cys-Tyr-Lys-Lys-Asp-Asn-Ile-Cys-Lys-Tyr-Lys-Ala-Gln -Ser-Gly-Lys-Thr-Ala-Ile-Cys-Lys-Cys-Tyr-Val-Lys-Lys-Cys-Pro-Arg-Asp-Gly-Al a-Lys-Cys-Glu-Phe-Asp-Ser-Tyr-Lys-Gly-Lys-Cys-Tyr-Cys can be produced by the fermentation of Aspergillus giganteus and used as an antifungal agent. Expression of this polypeptide gene in plants strongly inhibits the growth of phytopathogenic fungi on the plant.

Antifungal polypeptide and process for its production

The gene asnA which encodes a prokaryotic ammonium-specific asparagine synthetase (ASN-A) can be introduced into plant cells. Such transformed cells and plants developed therefrom not only tolerate glutamine synthetase inhibitors but are effectively stimulated by such herbicides.

Transgenic plants expressing a prokaryotic ammonium dependent asparagine

A multifunctional RNA having self-processing activity, the preparation thereof and the use thereof. Host cells can be transformed so that they express ribozyme RNA and antisense RNA which are connected with each other via a spacer. The RNA molecules can, for example, be complementary to a certain viral RNA. Plants which have been transformed with genes coding for RNA of this type show a significantly improved resistance to viruses.

The polypeptide with the sequence (SEQ ID NO: 1)

The phosphinothricin (PTC)-resistance gene isolated from the genome of Streptomyces viridochromogenes DSM 40736 is, after adaptation to the codon usage in plants, synthesized and incorporated into gene structures which make plants resistant to PTC after expression therein.

Phosphinothricin-resistance gene, and its use

Growing community of inventors

Kelkheim, Germany

Peter Eckes