Second Genome, Inc.

Peter DiStefano

Nadir A Mahmood

Rachel Steger

Nadir Mahmood

The disclosure provides assay methods for characterizing the effects of an agent on a microbiome of a subject. Moreover, the disclosure provides methods for practical applications of assay results. The biological sample is extracted and the microbial population is enumerated by using signals or markers specific to the microbial species. The enumerated population is subjected to the action of one or many therapeutic agents and the efficiency is assessed by deriving a score based on the effects in the individual samples and in the population of samples.

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Southborough, MA, United States of America

Peter DiStefano