Delsys Pharmaceutical Corporation

Sarnoff Corporation

Other

Peter David Southgate

William Ronald Roach

Peter John Zanzucchi

Nitin Vithalbhai Desai

David A Keller

Bawa Singh

Eugene Samuel Poliniak

Howard Christopher Rivenburg

Dominic Stephen Rosati

Nalin Kumar

Lawrence Harrison Hammer

Hoi Cheong Sun

Timothy Allen Pletcher

Aaron W Levine

Joseph Thomas McGinn

Zygmunt Marian Andrevski

Hoi Cheong Steve Sun

David Norman Ludington

Frank B Lang

Zvi Gerald Loewy

Suggy S Chrai

Ramaswamy Murari

Bogdan Brycki

Hoi Cheong (Steve) Sun

Prince Lal

Provided is an electrostatic sensing chuck for attracting particles to a portion of a particle contact surface near a deposition electrode, the electrostatic sensing chuck comprising a pixel comprising: a deposition electrode (DE) for selectively establishing an attraction field (E ) at the particle contact surface; a shield electrode (SE) oppositely biased with respect to the deposition electrode; a charge sensing circuit to measure charge accumulated on each of the deposition electrode and the shield electrode, wherein the charge sensing circuit subtracts a second charge it senses at the shield electrode from a first charge it senses at the deposition electrode, thereby determining accumulated charge at the deposition electrode balanced by accumulated charge at the shield electrode.

Electrostatic sensing chuck using area matched electrodes

Methods using dry powder deposition apparatuses

A substrate is roboticaly picked up at a station and transported to a measuring station to measure the distance to a reference. The substrate is aligned to a robot before measurement. The measured substrate is then transported to a pharmaceutical or diagnostic powder/grain deposition station where the powder/grains are controllably deposited on the substrate to predetermined thicknesses over a plurality of powder/grain collection zones. The deposited powder/grains are then measured to determine the thickness and area covered by the deposited powder/grains at each collection zone. The substrate is then transported to a lamination station and each collection zone of powder/grains is welded to a cover substrate. The system remembers which collection zones are out of specification so that they can be later selectively discarded.

Pharmaceutical product

Provided is, among other things, a dry deposition apparatus for depositing grains on a substrate comprising:

Dry powder deposition apparatus

The invention relates to an assay system for conducting elevated temperature reactions in a fluid-tight manner within a reaction chamber, the assay system comprising: (a) a first assembly comprising the reaction chamber, and (b) a second assembly for temperature control, wherein the second assembly can be positioned adjacent to the reaction chamber. More particularly, the invention relates to an assay system comprising (a) a reaction chamber having a cover formed of a deformable material and (b) a mechanism for rapidly adjusting the temperature of the reaction chamber.

Assay system and method for conducting assays

The present invention relates to a device and a method of use for that device for the automated preparation of nucleic acid from a biological sample. The device relates to a cassette in which all chemical manipulations occur, which includes a storage/transfer strip where the prepared nucleic acid is deposited and stored without contamination. Moreover, the waste of the preparation protocol is contained in the cassette, which, upon the separation of the filled storage/transfer strip is completely sealed off from the environment. In a preferred embodiment, the inventive device can prepare nucleic acid preparations from up to 24 different biological samples at a time.

Automated nucleic acid isolation

The invention provides a parallel reaction device for conducting reactions therein comprising one or more reaction flow-ways, each such reaction flow-way comprising one or more chambers connected serially by fluid exchange channels, additional fluid exchange channels connecting such reaction channels in parallel, valve means for initiating and impeding the flow of fluids through such fluid exchange channels, and means for moving the flow of fluids into and out of such chambers.

Parallel reaction cassette and associated devices

Growing community of inventors

Monmouth Junction, NJ, United States of America

Peter David Southgate