Priva Agro Holding B.v.

Stichting Centrum Voor Micro-elektronics Twente

Peter D Van Der Wal

David N Reinhoudt

Albert Van Den Berg

Jan R Haak

Ernst J Sudholter

Udo H Verkerk

Hermanus A Holterman

Gerardus W Honig

Maria D Skowronska-Ptasinska

An ionophore according to the general formula I wherein the substituents are chosen such that the ionophore is either also polymerized in the matrix of a membrane selective for metal ions or interwoven therewith. Thus obtained is a membrane having a long useful life for use in diverse sensors such as ISFET, ion-selective electrode, and the like.

Membrane selective for metal ions

The invention relates to a process for manufacturing a REFET and/or CHEMFET, comprising: (a) covalent bonding of a hydrophilic polymer layer to an isolator layer applied to a semiconductor material; (b) the absorption of water or a watery solution into said hydrophilic polymer layer; and (c) the binding of a hydrophobic polymer layer to the water holding hydrophilic polymer layer. It is advantageous that this water holding hydrophilic polymer layer also contains an electrolyte and/or a buffer. Preferably an ion to be measured with the CHEMFET also forms part of the electrolyte.

Process for manufacturing a REFET or a CHEMFET, and the manufactured

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Enschede, Netherlands

Peter D Van Der Wal