W. L. Gore & Associates, Inc.

Peter D Traylor

Edward H Cully

Elazer Reuven Edelman

Paul D Drumheller

Robert L Cleek

Mei Li

Charles David Claude

Mark D Edmundson

Minghua Xu

Peter Heicksen

Brett G Zani

Peter Markham

William E Strohben, Jr

Corey A Abrams

Rochitha R Nathan

Theresa Holland

Steven M Alston

Abraham Tzafriri

An electrochemical analyte biosensor is configured to detect an analyte. The electrochemical analyte biosensor includes a biocompatible electrode composite with a microporous polymer substrate having a plurality of interconnected pores, an electrically conductive region serving as a working electrode and including a conductive material contained at least partially in the interconnected pores of the microporous polymer substrate, and at least one immobilized bioreceptor region adjacent to the electrically conductive region. The conductive material may include a conformal metal coating on the microporous polymer substrate or a nanoporous metal imbibed into the microporous polymer substrate. The microporous polymer substrate may support tissue integration and/or tissue ingrowth in certain applications. The electrochemical analyte biosensor may be used in medical, industrial, agricultural, environmental, and other applications.

Electrochemical analyte biosensors, associated compositions of matter, and methods for making and using same

The present disclosure is directed toward composite materials comprising high aspect ratio habits of drug crystals which can be partially or fully extending into a substrate, and additionally, can be projecting from a substrate at an angle of about 20° to about 90°. The present disclosure is directed toward medical devices, such as medical balloons, comprising said composite and methods of using and making the same. The described composite can be used for the local treatment of vascular disease. The present disclosure is also directed toward paclitaxel crystals with a hollow acicular habit.

Porous composites with high-aspect ratio crystals

The present disclosure is directed toward composite materials comprising high aspect ratio habits of drug crystals which can be partially or fully extending into a substrate, and additionally, can be projecting from a substrate at an angle of about 20&#xb0; to about 90&#xb0;. The present disclosure is directed toward medical devices, such as medical balloons, comprising said composite and methods of using and making the same. The described composite can be used for the local treatment of vascular disease. The present disclosure is also directed toward paclitaxel crystals with a hollow acicular habit.

Growing community of inventors

Flagstaff, AZ, United States of America

Peter D Traylor