Biovitrum Ab

Volvo Penta Corporation

C2 Advisors Ab

Carlsson, Peter

Ainegren, Mats

Sandberg, Sten

Tinnsten, Mats

Peter Carlsson

Johan Tell

Lars Johansson

Sven Enerb&auml;ck

Mikael Hellberg

Mats Ainegren

Mats Tinnsten

Sten Sandberg

A marine propeller combination for a marine propulsion unit includes a first propeller and a second propeller arranged to rotate simultaneously in opposite directions about a common rotational axis. The marine propeller combination is configured such that the first and second propellers are angularly positioned such that during one revolution one of the blades of the first propeller is aligned with a drive leg of the marine propulsion unit when a blade gap of the second propeller is aligned with the drive leg, or one of the blades of the first propeller is aligned with the drive leg when one of the blades of the second propeller is aligned with the drive leg. The disclosure further relates to a marine vessel and to a method of operating a marine propeller combination.

Angularly positioned marine propeller combination and a method of operating a marine propeller combination

According to the invention, a major role for the winged helix protein FKHL14/FOXC2 in regulating energy balance and adiposity is demonstrated. The invention relates to transgenic non-human mammalian animals being capable of expressing the human FKHL14/FOXC2 gene in its adipose tissue. The invention also relates to methods for identifying compounds useful for the treatment of medical conditions related to obesity or diabetes, said compounds being capable of stimulating expression of the human FKHL14/FOXC2 gene, or being capable of stimulating the biological activity of a polypeptide encoded by the human FKHL14/FOXC2 gene. The invention further relates to methods for identifying compounds useful for the treatment of medical conditions related to malnutrition, said compounds being capable of decreasing expression of the human FKHL14/FOXC2 gene, or being capable of decreasing the biological activity of a polypeptide encoded by the human FKHL14/FOXC2 gene.

Animal model

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Floda, Sweden

Peter Carlsson