Dexcom, Inc.

Dex Com, Inc.

Peter C Simpson

Apurv Ullas Kamath

James H Brauker

Mark C Brister

Paul V Neale

Matthew D Wightlin

Jack Pryor

James R Petisce

Sebastian Bohm

Robert James Boock

Sean T Saint

Naresh Chandra Bhavaraju

Jason M Halac

Stephen J Vanslyke

Arturo Garcia

Jennifer Blackwell

Hari Hampapuram

Eli Reihman

Daiting Rong

Michael Robert Mensinger

John Michael Gray

Leif N Bowman

Katherine Yerre Koehler

Mark Allan Tapsak

Aarthi Mahalingam

Jacob S Leach

Michael J Estes

Paul V Goode, Jr

Sebastian Böhm

Mark Dervaes

Anna Leigh Davis

Jeff Jackson

Kenneth Pirondini

Philip Thomas Pupa

Maria Noel Brown Wells

Phong Lieu

Andrew Attila Pal

Shawn Larvenz

Justen Deering England

Aditya Sagar Mandapaka

John Nolting

Jason Mitchell

Rian W Draeger

Dubravka Markovic

Steve Masterson

Thomas Hall

Scott M Belliveau

Mark Douglas Kempkey

Vance Swanson

David A Keller

Lauren Hruby Jepson

Thomas Arnold Peyser

Jonathan Hughes

Victoria E Carr-Brendel

John Charles Barry

Gary A Morris

Alexandra Elena Constantin

Disha B Sheth

Kum Ming Woo

Laura J Dunn

Ted Tang Lee

Randall Scott Koplin

Phil Mayou

Mark C Shults

Ryan Everett Schoonmaker

Richard Chien Yang

Nicholas Polytaridis

Young Woo Lee

Patrick John Castagna

Warren Marc Terry

Monica A Rixman

Douglas William Burnette

Ying Li

Daniel Smith

Brian Christopher Smith

Esteban Cabrera, Jr

Eric Cohen

Antonio C Llevares

Andrew P Rasdal

James Patrick Thrower

Rathbun K Rhodes

Daniel Steven Kline

Paul D Kramer

Ben Xavier

John Michael Dobbles

Subrai Girish Pai

Neal Davis Johnston

Alan Baldwin

Tom Miller

Benjamin Elrod West

Becky L Clark

Christopher Robert Hannemann

Rui Ma

David Price

Kaushik Aroonkumar Patel

Jose Hector Hernandez-Rosas

Arnold Holmquist

Paul Noble-Campbell

Jorge Valdes

Huashi Zhang

Systems and methods of use involving sensors having a signal-to-noise ratio that is substantially unaffected by non-constant noise are provided for continuous analyte measurement in a host. In some embodiments, a continuous analyte measurement system is configured to be wholly, transcutaneously, intravascularly or extracorporeally implanted.

Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise

Certain embodiments herein relate to a physiological parameter monitoring system. The system may include a sensor and sensor electronics connectable to the sensor. The system may also include a transmitter operably connected to the sensor electronics, the transmitter having or being configured to have at least a portion thereof positioned at a first location adjacent to and/or in contact with an external surface of a body of a host during a sensor session, the transmitter further configured to wirelessly transmit sensor information using human body communication. The system may further include a first display device comprising a display and a receiver, the receiver having or being configured to have at least a portion thereof positioned at a second location adjacent to and/or in contact with the external surface of the body during the sensor session, the receiver further configured to receive sensor information from the transmitter using human body communication.

Network physical layer configurations for ambulatory physiological parameter monitoring and therapeutic intervention systems

Various analyte sensor systems for controlling activation of analyte sensor electronics circuitry are provided. Related methods for controlling analyte sensor electronics circuitry are also provided. Various analyte sensor systems for monitoring an analyte in a host are also provided. Various circuits for controlling activation of an analyte sensor system are also provided. Analyte sensor systems utilizing a state machine having a plurality of states for collecting a plurality of digital counts and waking a controller responsive to a wake up signal are also provided. Related methods for such analyte sensor systems are also provided. Systems for controlling activation of analyte sensor electronics circuitry utilizing a magnetic sensor are further provided. One or more display device configured to display one or more analyte concentration values are also provided.

Systems and method for activating analyte sensor electronics

Systems and methods for analyte monitoring, particularly systems and methods for monitoring and managing life of a battery in an analyte sensor system worn by a user, are provided.

Systems and methods for monitoring and managing life of a battery in an analyte sensor system worn by a user

Adhesive pad systems that provide longer lasting adherence of the mounting unit to the host's skin are provided. Some systems include a reinforcing overlay that at least partially covers the adhesive pad. The reinforcing overlay may be removable without disturbing the sensor so that the overlay may be replaceable.

Systems and methods for securing a continuous analyte sensor to a host

Systems and methods described provide dynamic and intelligent ways to change the required level of user interaction during use of a monitoring device. The systems and methods generally relate to real time switching between a first or initial mode of user interaction and a second or new mode of user interaction. In some cases, the switching will be automatic and transparent to the user, and in other cases user notification may occur. The mode switching generally affects the user's interaction with the device, and not just internal processing. The mode switching may relate to calibration modes, data transmission modes, control modes, or the like.

System and method for mode switching

Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

Advanced analyte sensor calibration and error detection

Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

Analyte sensor

The present invention relates generally to systems and methods for processing, transmitting, and displaying data received from continuous analyte sensor, such as a glucose sensor. In some embodiments, the continuous analyte sensor system comprises a sensor electronics module that includes power saving features. One feature includes a low power measurement circuit that can be switched between a measurement mode and a low power mode, in which charging circuitry continues to apply power to electrodes of a sensor during the low power mode. In addition, the sensor electronics module can be switched between in a low power storage mode higher power operational mode via a switch. The switch can include a reed switch or optical switch, for example. A validation routine can also be implemented to ensure an interrupt signal sent from the switch is valid. The continuous analyte sensor can be physically connected to a sensor electronics module, which is in direct wireless communication with a plurality of different display devices.

Advanced continuous analyte monitoring system

Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

System and method for providing alerts optimized for a user

Systems and methods are provided to calibrate an analyte concentration sensor within a biological system, generally using only a signal from the analyte concentration sensor. For example, at a steady state, the analyte concentration value within the biological system is known, and the same may provide a source for calibration. Similar techniques may be employed with slow-moving averages. Variations are disclosed.

Transcutaneous analyte sensors and monitors, calibration thereof, and associated methods

Systems for applying a transcutaneous monitor to a person can include a telescoping assembly, a sensor, and a base with adhesive to couple the sensor to skin. The sensor can be located within the telescoping assembly while the base protrudes from a distal end of the system. The system can be configured to couple the sensor to the base by compressing the telescoping assembly.

Transcutaneous analyte sensor systems and methods

Systems and methods are provided that address the need to frequently calibrate analyte sensors, according to implementation. In more detail, systems and methods provide a preconnected analyte sensor system that physically combines an analyte sensor to measurement electronics during the manufacturing phase of the sensor and in some cases in subsequent life phases of the sensor, so as to allow an improved recognition of sensor environment over time to improve subsequent calibration of the sensor.

Automatic analyte sensor calibration and error detection

Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.

Integrated delivery device for continuous glucose sensor

Growing community of inventors

Cardiff, CA, United States of America

Peter C Simpson