Dexcom, Inc.

Dex Com, Inc.

Peter C Simpson

Apurv Ullas Kamath

James H Brauker

Mark C Brister

Paul V Neale

Matthew D Wightlin

Jack Pryor

James R Petisce

Sebastian Bohm

Robert James Boock

Sean T Saint

Naresh Chandra Bhavaraju

Jason M Halac

Stephen J Vanslyke

Arturo Garcia

Jennifer Blackwell

Hari Hampapuram

Daiting Rong

Eli Reihman

John Michael Gray

Michael Robert Mensinger

Leif N Bowman

Katherine Yerre Koehler

Mark Allan Tapsak

Aarthi Mahalingam

Jacob S Leach

Michael J Estes

Sebastian Böhm

Paul V Goode, Jr

Mark Dervaes

Anna Leigh Davis

Kenneth Pirondini

Jeff Jackson

Maria Noel Brown Wells

Philip Thomas Pupa

Phong Lieu

Justen Deering England

Andrew Attila Pal

Shawn Larvenz

Aditya Sagar Mandapaka

John Nolting

Mark Douglas Kempkey

Rian W Draeger

Dubravka Markovic

Steve Masterson

David A Keller

Thomas Hall

Scott M Belliveau

Vance Swanson

Lauren Hruby Jepson

Thomas Arnold Peyser

John Charles Barry

Jonathan Hughes

Victoria E Carr-Brendel

Gary A Morris

Alexandra Elena Constantin

Disha B Sheth

Kum Ming Woo

Laura J Dunn

Ted Tang Lee

Randall Scott Koplin

Phil Mayou

Young Woo Lee

Patrick John Castagna

Mark C Shults

Ryan Everett Schoonmaker

Richard Chien Yang

Nicholas Polytaridis

Warren Marc Terry

Andrew C Joncich

Alan Baldwin

Monica A Rixman

Douglas William Burnette

Ying Li

Neal Davis Johnston

Tom Miller

Daniel Smith

Benjamin Elrod West

Becky L Clark

Brian Christopher Smith

Esteban Cabrera, Jr

Rui Ma

David Price

Eric Cohen

Antonio C Llevares

Andrew P Rasdal

James Patrick Thrower

Rathbun K Rhodes

Daniel Steven Kline

Paul D Kramer

Jorge Valdes

Nelson Quintana

John Michael Dobbles

Christopher Robert Hannemann

Kaushik Aroonkumar Patel

Jose Hector Hernandez-Rosas

Arnold Holmquist

Paul Noble-Campbell

Ben Xavier

Huashi Zhang

Disclosed herein are devices, systems, and methods for a continuous analyte sensor, such as a continuous glucose sensor. In certain embodiments disclosed herein, various in vivo properties of the sensor's surroundings can be measured. In some embodiments, the measured properties can be used to identify a physiological response or condition in the body. This information can then be used by a patient, doctor, or system to respond appropriately to the identified condition.

Implantable sensor devices, systems, and methods

The present embodiments relate generally to applicators of on-skin sensor assemblies for measuring an analyte in a host, as well as their method of use and manufacture. In some aspects, an applicator for applying an on-skin sensor assembly to a skin of a host is provided. The applicator includes an applicator housing, a needle carrier assembly comprising an insertion element configured to insert a sensor of the on-skin sensor assembly into the skin of the host, a holder releasably coupled to the needle carrier assembly and configured to guide the on-skin sensor assembly while coupled to the needle carrier assembly, and a drive assembly configured to drive the insertion element from a proximal starting position to a distal insertion position, and from the distal insertion position to a proximal retraction position.

Transcutaneous analyte sensors, applicators therefor, and associated methods

Systems and methods of use involving sensors having a signal-to-noise ratio that is substantially unaffected by non-constant noise are provided for continuous analyte measurement in a host. In some embodiments, a continuous analyte measurement system is configured to be wholly, transcutaneously, intravascularly or extracorporeally implanted.

Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise

Certain embodiments herein relate to a physiological parameter monitoring system. The system may include a sensor and sensor electronics connectable to the sensor. The system may also include a transmitter operably connected to the sensor electronics, the transmitter having or being configured to have at least a portion thereof positioned at a first location adjacent to and/or in contact with an external surface of a body of a host during a sensor session, the transmitter further configured to wirelessly transmit sensor information using human body communication. The system may further include a first display device comprising a display and a receiver, the receiver having or being configured to have at least a portion thereof positioned at a second location adjacent to and/or in contact with the external surface of the body during the sensor session, the receiver further configured to receive sensor information from the transmitter using human body communication.

Network physical layer configurations for ambulatory physiological parameter monitoring and therapeutic intervention systems

Various analyte sensor systems for controlling activation of analyte sensor electronics circuitry are provided. Related methods for controlling analyte sensor electronics circuitry are also provided. Various analyte sensor systems for monitoring an analyte in a host are also provided. Various circuits for controlling activation of an analyte sensor system are also provided. Analyte sensor systems utilizing a state machine having a plurality of states for collecting a plurality of digital counts and waking a controller responsive to a wake up signal are also provided. Related methods for such analyte sensor systems are also provided. Systems for controlling activation of analyte sensor electronics circuitry utilizing a magnetic sensor are further provided. One or more display device configured to display one or more analyte concentration values are also provided.

Systems and method for activating analyte sensor electronics

Systems and methods for analyte monitoring, particularly systems and methods for monitoring and managing life of a battery in an analyte sensor system worn by a user, are provided.

Systems and methods for monitoring and managing life of a battery in an analyte sensor system worn by a user

Adhesive pad systems that provide longer lasting adherence of the mounting unit to the host's skin are provided. Some systems include a reinforcing overlay that at least partially covers the adhesive pad. The reinforcing overlay may be removable without disturbing the sensor so that the overlay may be replaceable.

Systems and methods for securing a continuous analyte sensor to a host

Systems and methods described provide dynamic and intelligent ways to change the required level of user interaction during use of a monitoring device. The systems and methods generally relate to real time switching between a first or initial mode of user interaction and a second or new mode of user interaction. In some cases, the switching will be automatic and transparent to the user, and in other cases user notification may occur. The mode switching generally affects the user's interaction with the device, and not just internal processing. The mode switching may relate to calibration modes, data transmission modes, control modes, or the like.

System and method for mode switching

Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

Advanced analyte sensor calibration and error detection

Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

Analyte sensor

The present invention relates generally to systems and methods for processing, transmitting, and displaying data received from continuous analyte sensor, such as a glucose sensor. In some embodiments, the continuous analyte sensor system comprises a sensor electronics module that includes power saving features. One feature includes a low power measurement circuit that can be switched between a measurement mode and a low power mode, in which charging circuitry continues to apply power to electrodes of a sensor during the low power mode. In addition, the sensor electronics module can be switched between in a low power storage mode higher power operational mode via a switch. The switch can include a reed switch or optical switch, for example. A validation routine can also be implemented to ensure an interrupt signal sent from the switch is valid. The continuous analyte sensor can be physically connected to a sensor electronics module, which is in direct wireless communication with a plurality of different display devices.

Advanced continuous analyte monitoring system

Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

System and method for providing alerts optimized for a user

Systems and methods are provided to calibrate an analyte concentration sensor within a biological system, generally using only a signal from the analyte concentration sensor. For example, at a steady state, the analyte concentration value within the biological system is known, and the same may provide a source for calibration. Similar techniques may be employed with slow-moving averages. Variations are disclosed.

Transcutaneous analyte sensors and monitors, calibration thereof, and associated methods

Systems for applying a transcutaneous monitor to a person can include a telescoping assembly, a sensor, and a base with adhesive to couple the sensor to skin. The sensor can be located within the telescoping assembly while the base protrudes from a distal end of the system. The system can be configured to couple the sensor to the base by compressing the telescoping assembly.

Transcutaneous analyte sensor systems and methods

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Cardiff, CA, United States of America

Peter C Simpson