Albany Molecular Research, Inc.

Amr Technology, Inc.

Teewinot Life Sciences Corporation

Other

Teewinot Technologies Limited

Enzymed, Inc.

Peter C Michels

Malcolm J Kavarana

Richard C Peet

C Seth Pearson

Geoffrey M Fox

John D Rabenstein

Eric L Zirbes

Jonathan S Dordick

Douglas S Clark

Zhicai Yang

Mingyang Sun

Yuri L Khmelnitsky

Bruce Francis Molino

David Douglas Manning

Jordan U Gutterman

Cheng Guo

Valsala Haridas

Michael S Hemenway

Jun-Ho Maeng

Simon N Haydar

Matthew W Chase

Joseph O Rich

Yuri Khmelnitsky

Grant J Carr

Vadim M Mozhaev

The disclosure provides systems and methods for producing a cannabinoid product, which comprises contacting a cannabinoid precursor in a first phase with a cannabinoid synthase in a second phase, wherein the first phase and the second phase are substantially immiscible or immiscible. The disclosure also provides a composition comprising the cannabinoid precursor in a first phase and a cannabinoid synthase in a second phase, wherein the first phase and the second phase are substantially immiscible or immiscible.

Apparatus, methods and composition for synthesis of cannabinoid compounds

Disclosed herein are novel oxetane derivatives of avicin D, including compounds of the formula (I), wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising these derivative compounds. Methods and intermediates useful for making the derivatives, and methods of using the derivatives and compositions thereof, including for the treatment of cancer, are also provided.

Derivatives of avicin D and methods of making and using thereof

The present invention relates to novel therapeutics with antibacterial activity, processes for their preparation, and pharmaceutical, veterinary and nutritional compositions containing them as active ingredients. The present invention also relates to uses of the novel therapeutics, for example, as medicants or food additives in the treatment of bacterial infections or to aid body mass gain in a subject.

Antibacterial compounds, methods of making them, and uses thereof

The present invention relates to the production of a product compound having a structure according to Formulae IA and/or IB:  This process involves incubating a starting compound having a structure according to Formulae IIA and/or IIB: 

Process for the production of piperidine derivatives with microorganisms

The compounds of the present invention are represented by the chemical structure found in Formula I: where A is an amino acid of Formula II: or a pharmaceutically acceptable salt thereof, with R, R, B, C, D, E, F, G, H, I, J, and K defined herein.

Cyclosporins

The present invention relates to a process for the production of piperidine derivatives with microorganisms. This is carried out by incubating starting compounds in the presence of a microorganism under conditions effective to produce piperidine derivative products. Suitable microorganisms can be from any one of the genus of, and. In another aspect of the invention, starting compounds are incubated in the presence ofunder conditions effective to produce piperidine derivative products.

Highly specific biocatalytic reactions have been used to create a population of taxol derivatives.

Taxol derivatives

Biocatalytic methods for synthesizing and identifying biologically

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Voorheesville, NY, United States of America

Peter C Michels