Novartis Ag

Novartis Pharma Gmbh

Peter Buehlmayer

Gebhard Thoma

Maurice Van Eis

Klaus Hinterding

Rudolf Duthaler

Nigel Graham Cooke

Gerhard Zenke

Anette Von Matt

Rolf Baenteli

Marie Claude Bernhard

Louis Walliser

Manuel Koller

Carsten Spanka

Erwin Marti

Alexander Baxter Smith

Frédéric Zecri

Wolfgang Marterer

Rochdi Bouhelal

Hans Rudolf Oswald

Danilo Guerini

Kamal Azzaoui

Nigel Cooke

Marie Bernhard

The invention relates to new salts of valsartan or crystalline, also partly crystalline and amorphous salts of valsartan, the respective production and usage, and pharmaceutical preparations containing such a salt.

Valsartan salts

The present invention relates to bicyclic heteroaryl cycloalkyldiamine derivatives, to processes for their production, to their use as SYK inhibitors and to pharmaceutical compositions comprising them. Formula (I) 

Bicyclic heteroaryl cycloalkyldiamine derivatives

Disclosed are pyrimidine derivatives of formula wherein R, R, Rto R, and Z have a signification as indicated in claim, which have interesting pharmaceutical properties.

2,4- Di(hetero)-arylamino-pyrimidine derivatives as ZAP-70 and/or SYK inhibitors

The present invention relates to agonists of the S1P4 receptor, which are selective for the S1P4 receptor over one or more of the S1P1, S1P2, S1P3 or S1P5 receptors of at least 10 fold, in particular new indol-alanine derivatives of structure I, process for their production, their uses, in particular in transplantation, and pharmaceutical compositions containing them wherein

Indol-alanine derivatives as selective S1P4-agonists

Disclosed are pyrimidine derivatives of formula wherein R, R, Rto R, and Z have a signification as indicated in claimwhich have interesting pharmaceutical properties.

2,4 Di (hetero) -arylamino-pyrimidine derivatives as ZAP-70 and/or syk inhibitors

Compounds of formula I wherein R, R, R, Rand Rare as defined in the specification, processes for their production, their uses and pharmaceutical compositions containing them.

Amino-propanol derivatives

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Arlesheim, Switzerland

Peter Buehlmayer