Other

Mcneil-ppc, Inc.

Mcneil-pcc, Inc.

Peter Britton

William P Hart

Patricia C Flanagan

Deborah Linkin

The invention relates to a muco-adherent, soluble device for administering active ingredients, a method of using said device, and an improved method of manufacturing said device using a continuous, enclosed mixing device capable of operating under pressure. The devices of the invention, which comprise a lyophilized foam and an active ingredient, have a dissolution time of at least about 8 hours, and preferably at least about 24 hours, and can provide for the sustained and/or controlled release of an active ingredient for up to about 24 hours.

Bioerodible device for administering active ingredients

The invention relates to an intravaginally-dissolvable contraceptive suppository, a method of using said suppository, and an improved method of manufacturing said birth control device. The suppositories of the invention, which comprise a lyophilized foam and a contraceptive, have a dissolution time of at least about 2 hours, and up to about 24 hours, and provide superior protection against pregnancy.

Bioerodible contraceptive suppository

Method for manufacturing buccal delivery device

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Scotch Plains, NJ, United States of America

Peter Britton