Senetek Plc

Koninklijke Philips Corporation N.v.

Icn Photonics Limited

Christiansen, Kåre

Bjerring, Peter

Van Der Beek, Klaas

Peter Bjerring

Robbert Adrianus Maria Van Hal

Robert Marc Clement

Peter K Jensen

Lars Bolund

Michiel Errit Roersma

Bernardus Leonardus Gerardus Bakker

Klaas Van Der Beek

Kåre Christiansen

The invention relates to a device () for treating human skin by means of radiation. The device has a housing () with a radiation exit opening (), a radiation source () which is accommodated in the housing, and a radiation path () between the radiation source and the radiation exit opening. A radiation filter () is provided in the radiation path. According to the invention the radiation filter () comprises water () which is in solid state at least during an initial phase of operation of the device (). The water in solid state has an optical transmission spectrum which corresponds to the optical transmission spectrum of water in liquid state as present in the skin. As a result the water in solid state acts as an ideal filter for the IR light and near IR light, which would otherwise be absorbed by the water in the skin and cause unwanted heating of the skin. An additional advantage of the water in solid state is its relatively high heat absorbing capacity and its ability to cool the skin in case of direct thermal contact with the skin. In a particular embodiment the device () is an epilator for the removal of hairs from the human skin, the radiation source () being a flash lamp which generates light pulses having a high energy density and a broad optical spectrum.

Device for treating human skin by means of radiation

It has been discovered that 6-(substituted amino)purine cytokinins, such as kinetin, induce differentiation, and consequently reduce or eliminate the abnormally high rate of proliferation, of hyperproliferating cells associated with hyperproliferative skin diseases. Thus, the present invention provides methods and compositions for treating hyperproliferative skin diseases in mammals, particularly such diseases associated with hyperproliferating epidermal cells in humans, by administering to the hyperproliferating cells associated with such a disease, in the skin of a mammal suffering therefrom, a differentiation-inducing effective amount of a 6-(substituted amino)purine cytokinin. 87

Method for treating hyperproliferative skin diseases

It has been discovered that 6-(substituted amino)purine cytokinins, such as kinetin, induce differentiation, and consequently reduce or eliminate the abnormally high rate of proliferation, of hyperproliferating cells associated with hyperproliferative skin diseases, such as psoriasis. Thus, the present invention provides methods and compositions for treating hyperproliferative skin diseases in mammals, particularly such diseases associated with hyperproliferating epidermal cells in humans, by administering to the hyperproliferating cells associated with such a disease, in the skin of a mammal suffering therefrom, a differentiation-inducing effective amount of a 6-(substituted amino)purine cytokinin.

Method and composition for treating hyperproliferative skin diseases

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Risskov, Denmark

Peter Bjerring