Boehringer Mannheim Gmbh

Peter Bialk

Herbert Von Der Eltz

Christoph Seidel

Helmut Lenz

Nicholas R Hoyle

Helmut Rehner

Peter Stegmuller

Albert Kunst

A conjugate of at least two binding sites that bind specifically to the analyte-specific binding region of the receptor that is used for detection in a test, wherein the binding sites are linked by at least one soluble carrier substance and the conjugate is a product of a synthetic or recombinant production, dissolved in an aqueous solution in an exactly known amount is particularly suitable as a stable calibrator in a test for the detection of an analyte.

Synthetic standard for immunoassays

A standard solution containing thyroxine-binding globulin (TBG) and thyroxine or triiodothyronine dissolved in a buffer solution is used for calibration in a method for the determination of thyroxine (T.sub.4) or triiodothyronine (T.sub.3) in serum, wherein both human and bovine TBG can be used.

Method and standard solution for the determination of thyroxine

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Eberfing, Germany

Peter Bialk