Lake Region Manufacturing, Inc.

Ndsu-Research Foundation

Lake Region Manufacturing, Inc. D/b/a Lake Region Medical

Peter Anthony Edwards

Dean C Webster

Umesh D Harkal

Andrew J Muehlberg

A coating composition containing added diol functionality to a urethane, a urea, or polyurethane urea functional resin where an adipic acid dihydrazide chain extender, or free adipic acid dihydrazide active hydrogens react with the oxirane group found in glycidol is described. The combination of diisocyanate, a polyether segment, optionally at least one polyester diol segment, optionally at least one poly(tetrahydrofuran) diol segment, optionally and at least one dimethylol propionic acid diol segment, at least one dihydrazide segment and glycidol compound introduces an increased hydrophilic structure, by diol addition, in compositions that are usable as coatings, on for example, medical devices.

Polyurethane urea-containing adipic acid dihydrazide coating where active hydrogens react with the glycidol epoxy group to form a diol

Polyurethane urea-containing adipic acid dihydrazide where active hydrogens react with the epoxy group found on glycidol to form a diol

The present invention relates to hydrophilic, i.e., water loving coatings (hereafter referred to as 'WLC'). Polyurethane epoxy alkylene oxide coatings usable as coatings on for example, medical devices are a preferred WLC.

Oxirane (ethylene oxide) polyurethane coatings

The invention relates to novel aqueous coating compositions containing epoxy urethane (glycidyl carbamate) functional resin. An aqueous coating composition comprises a polyfunctional oligomer having at least two epoxy urethane functional groups and a polyalkylene oxide chain, an optional surfactant, and water. The aqueous coating compositions of the invention can be dispersed in water with or without added surfactants to form a dispersion containing no volatile organic solvent. The invention provides a method for making aqueous coating compositions containing epoxy urethane functional resin as well. Water-dispersible epoxy urethane compounds of the aqueous coating compositions are also provided.

Water dispersible epoxy urethane compounds and coating compositions

This invention relates to hydrophilic polymer compositions and a preferred application therefore, viz., hydrophilic medical device coatings. The hyaluronic acid hyaluronon by itself or modified as described herein advantageously reacts with compositions disclosed in U.S. Pat. No. 7,776,956 to produce hydrophilic compositions and coatings particularly useable with medical devices.

Modified hyaluronate hydrophilic compositions, coatings and methods

The invention relates to novel aqueous coating compositions containing epoxy urethane (glycidyl carbamate) functional resin. An aqueous coating composition comprises a polyfunctional oligomer having at least two epoxy urethane functional groups and a polyalkylene oxide chain, a surfactant and water. The aqueous coating compositions of the invention can be dispersed in water with added surfactants to form a dispersion containing no volatile organic solvent. The invention provides a method for making aqueous coating compositions containing epoxy urethane functional resin as well. Water-dispersible epoxy urethane compounds of the aqueous coating compositions are also provided.

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Cokato, MN, United States of America

Peter Anthony Edwards