Allergan, Inc.

Akrivista LLC

Peter A Simmons

Joseph G Vehige

Michael E Garst

Orest Olejnik

Scott M Whitcup

Wendy M Blanda

Joan-En Chang-Lin

David A Marsh

Steven S Matsumoto

Bereth J Beard

Liu Haixia

In preferred embodiments the invention is directed to ocular compositions for the treatment of dry eye, methods for making such compositions, and suites comprising a plurality of different ocular compositions each having a defined composition. In preferred examples, the invention is directed to compositions comprising at least one natural oil, wherein a first member of the suite of compositions is effective in treating dry in in a first patient having a particular set of symptoms and a different second member of the suite of compositions is effective in treating dry in in a second patient having a different set of symptoms. The invention is also directed to methods of making and using the compositions, and to skin care compositions for use around the eye, such as the upper and lower eyelids having a lubricating, non-irritating base composition comprising at least one natural oil.

Methods of diagnosing and treating dry eye syndrome and compositions for treating a human eye

Provided herein are low salt ophthalmic pharmaceutical composition and methods of use thereof, for example, in the treatment of dry eye syndrome.

Efficient lipid delivery to human tear film using a salt-sensitive emulsion system

Ophthalmic compositions including compatible solute components and/or polyanionic components are useful in treating eyes, for example, to relieve dry eye syndrome, to protect the eyes against hypertonic insult and/or the adverse effects of cationic species on the ocular surfaces of eyes and/or to facilitate recovery from eye surgery.

Ophthalmic compositions and methods for treating eyes

The present invention relates to ophthalmic compositions and methods useful to treat dry eye, or to diagnose, cure, mitigate, treat, or prevent dry eye syndrome in man or other animals.

Compositions for the treatment of dry eye

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Yorba Linda, CA, United States of America

Peter A Simmons