Hoechst Roussel Pharmaceuticals

Hoechst Marion Roussel

Aventis Pharmaceuticals Inc.

Other

Peter A Nemoto

Edward J Glamkowski

Yulin Chiang

Joseph T Strupczewski

John J Tegeler

Kenneth J Bordeau

Grover C Helsley

Lawrence L Martin

David G Wettlaufer

Raymond W Kosley, Jr

Denise M Flanagan

Gert U Kuerzel

Mark G Palermo

Gregory M Shutske

Richard C Effland

Larry A Davis

Joseph T Klein

Gordon E Olsen

John J Tegler

Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents. the compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one of the compounds. Depot derivatives of the compounds are useful for providing long acting effects of the compounds. The compounds are also useful as analgesics by administering a pain-relieving effective amount of one of the compounds to a mammal.

Heteroarylpiperidines and their use as antipsychotics

Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents. The compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one of the compounds. Depot derivatives of the compounds are useful for providing long acting effects of the compounds. The compounds are also useful as analgesics by administering a pain-relieving effective amount of one of the compounds to a mammal.

1-(aryloxyalkyl)-4-(heteroaryl) piperazines and related compounds useful as antipsychotics and analgesics

Heteroarylpiperidines and their use as antipsychotics and analgesics

N-&lsqb;(3-heteroaryl-1-pyrrolidinyl)-alkyl&rsqb;phthalimides and related compounds and their therapeutic utility

Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents the compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one of the compounds. Depot derivatives of the compounds are useful for providing long acting effects of the compounds. The compounds are also useful as analgesics by administering a pain-relieving effective amount of one of the compounds to a mammal.

3-heteroaryl-1-pyrrolidinealkylamines and derivatives thereof and their

This invention relates to compounds of the formula wherein X, Y, Z, m, n and p are as defined within, pharmaceutical compositions containing these compounds and to their use as antipsychotic agents, particularly in the treatment of schizophrenia. Depot derivatives of the compounds are useful for providing long acting effects of the compounds.

Antipsychotic agents, compositions and method of use

N-[(4-heteroaryl-1-piperazinyl) alkyl]phthalimides and related compounds

4-heteroaryl-1-piperazine alkylamines and their therapeutic utility

N-[(4-Heteroaryl-1-Piperidinyl)Alkly] Phthalimides and related compounds

1-[(2-pyrimidinyloxy)alkyl]4-(heteroaryl)piperazines and related

This invention relates to compounds of the formula ##STR1## wherein X, Y, Z, m, n and p are as defined within, pharmaceutical compositions containing these compounds and to their use as antipsychotic agents, particularly in the treatment of schizophrenia. Depot derivatives of the compounds are useful for providing long acting effects of the compounds.

4-heteroaryl-1-piperidinealkanols and derivatives thereof and their

Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents, the compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one of the compounds. Depot derivatives of the compounds are useful for providing long acting effects of the compounds. The compounds are also useful as analgesics by administering a pain-relieving effective amount of one of the compounds to a mammal.

4-heteroaryl-1-piperazinealkylthiols and derivatives thereof and their

4-heteroaryl-1-piperazinealkanols and derivatives thereof and their

3-heteroaryl-1-pyrrolidinealkylthiols and derivatives thereof and their

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Raritan, NJ, United States of America

Peter A Nemoto