Merck Sharp + Dohme Corp.

Schering Corporation

Schneider Gmbh

Peter A Basile

Steven Carl Persak

Jeffrey C Givand

Sharad Gupta

Ari Tao Adler

Christin L O'Neill

Robert Stianchi

Angela M Amend Kwasnik

Philip G Green

Scott R Mackie

Martin Meier

Florian Altmann

Thomas Junk

Florian Kössler

Pernilla Danielsson

Henry J Mack, Jr

Benjamin R Bartfeld

Stephen G Miggels

Oliver J Sha

Mikhail Gotliboym

Scott Robert Brown

Stephen Gerard Miggels

Brad Britland

Benjamin R Bartfield

Matthew Thomas Yurek

Robert L Berger

Henry Mack

Michael L Turini, Jr

Liann M Johnson

Wail A Rasheed

Michael M Maia

Inyoung Jang

Michael Galluppi

Robert Berger

Lawrence R Heyn

Scott Brown

Jr Henry J Mack

The present invention relates to drug delivery systems that cannot be reloaded or reused and further include a passive safety shield system. The drug delivery devices described herein comprise a drug container comprising at least one bellow, wherein the at least one bellow comprises a first surface and an opposing second surface, wherein the first surface is comprised of a first Belleville spring and the opposing second surface is comprised of a second Belleville spring, wherein the second Belleville spring has a higher spring rate than the first Belleville spring; or a drug container extending between distal and proximal ends, and comprises a continuous change in cross section from proximal end to distal end; a needle, wherein the needle is in liquid communication with the drug container; a plunger extending between a proximal end and a distal end, wherein the plunger is in communication with the drug container and where upon axial movement of the punger, the drug container is compressed; a main body extending between a proximal end and a distal end and comprising an inner body and an outer body, wherein the inner body houses the plunger and the drug container and the outer body is capable of sliding over the inner body and extending past the needle; and a spring located between the inner body and the outer body for urging the outer body to slide over the inner body and extend past the needle.

Prefilled disposable injection device

A manually actuated drug-injecting device is configured such that the grip strength of the entire hand (i.e., majority of fingers closing toward the palm or heel of the hand) is employed to discharge medication through a hypodermic needle and into a patient's body. The device is well suited for delivering medications with high viscosity and/or by patients (e.g., elderly patients) with reduced finger strength and dexterity. The device includes a grip member, a push member (which causes the medication to be injected), and a force-transfer mechanism that couples the grip member to the push member. Suitably, the device is configured to be held transverse to the palm of the medication-administering hand, with a discharge port located by the outer, blade edge of the administering hand, when the device is being gripped to administer medication.

Manually-actuated injection device for high-viscosity drugs

A reusable safety syringe training device is provided. The device comprises a syringe contained within a syringe protective member. The syringe protective member is movable vertically within an outer protective sheath from a first position to a second position and back to the first position. In the first position, the device is in an injection-ready position with the needle exposed and the syringe protective member in a locked vertical position with respect to the outer protective sheath. In the second position, the device is in a post-injection position such that the syringe protective member is no longer vertically locked with respect to the outer protective sheath and has moved vertically upward thereby rendering the needle within the outer protective sheath. The plunger carries a release flange sufficient to engage release latches that otherwise retain the syringe protective member in the first position. The release flange engages that release latches when the user pushes the plunger down to effectuate the injection. Once pressure is removed from the plunger after the injection has concluded, a springe mechanism drives the syringe protective member upwards to the second position. The user can then turn the plunger such that the release flange is no longer able to engage the release latches and push the plunger back down to lock the syringe protective member in its first position. The user is then able to pull the plunger back up while the syringe protective member remains locked, turn the plunger back to a position where the release flange is in a position to engage the release latches again, and perform another injection.

Patient training device for use with a safety syringe injector

An injector for delivering liquid can include a body having a proximal end, a distal end, a longitudinal axis, and a track follower adjacent to the proximal end. A plunger can be disposed at least partially within the body and movable with respect to the body along the longitudinal axis. An actuator can be positioned at the proximal end of the body and operably connected to the plunger. The actuator can include a track having a first portion and a second portion. The first portion can limit travel of the actuator along the longitudinal axis to deliver a first predetermined amount of the liquid. The second portion can limit travel of the actuator along the longitudinal axis to deliver a second predetermined amount of the liquid. The actuator can be positionable to selectively control displacement of the plunger pursuant to the first portion or the second portion of the track.

Metering injector for delivering liquid, and method of using same

The present invention relates to drug delivery systems that cannot be reloaded or reused and further include a passive safety shield system. The drug delivery devices described herein include a drug container comprising at least one bellow, a needle, wherein the needle is in liquid communication with the drug container; a plunger extending between a proximal end and a distal end, wherein the plunger is in communication with the drug container and where upon axial movement of the plunger, the drug container is compressed.

The present invention relates to a drug delivery device comprising a drug container having at least one bellow. The at least one bellow has a first surface and an opposing second surface. The first surface is comprised of a first Belleville spring and the opposing second surface is comprised of a second Belleville spring, wherein the second Belleville spring has a higher spring rate than the first Belleville spring.

A drug delivery device comprising a main body extending between distal and proximal ends comprising a hollow cylinder comprising an outer and an inner surface, wherein the inner surface comprises threads; a screw within the main body, comprising a hollow cylinder comprising an inner and an outer surface, wherein said outer surface comprises threads, wherein threads of outer surface of the screw are engaged with threads of inner surface of the main body; a plunger extending between distal and proximal ends, wherein the distal end of the plunger engages the proximal end of the screw; and a drug container extending between distal and proximal ends, and comprising a change in cross section from proximal to distal end, wherein the container is within the screw, and wherein the proximal end of the drug container is fixed to the screw and distal end of the container is fixed to the main body.

Medical injector pen

A medication injector that has an alert indicator that alerts the user when the medication injector is approaching near the end of its medication supply is disclosed. The alert indicator gives the user an opportunity to make preparations to obtain additional medication for the injector if there is an insufficient amount of medication in the injector to enable the user to dispense the required dosage amount with the next injection. Initially, the alert indicator is not visible to the user, but becomes visible to the user when the injector is near empty.

Medication injector with near-empty alert

Auto injector

Growing community of inventors

Bloomsbury, NJ, United States of America

Peter A Basile