Ge Healthcare Bio-sciences Ab

Cytiva Sweden Ab

Per Karlberg

Erik Rurling

Joakim Lundkvist

Joakim Svensson

Bengt Niklas Edblad

Mikael Bjorling

Jonas Karlsson

Mikael Björling

A method and a slurry tank system for transferring chromatography media slurry from a slurry tank () to a chromatography column (), said method comprising monitoring the content of slurry in the slurry tank () during the transferring and controlling the transferring of the slurry to the column () in dependence of the content of slurry in the slurry tank ().

Method for transferring slurry

A method for packing a media bed in a column (). According to the invention the method comprises the steps of: providing data to a control unit () connected to the column (), said data comprising at least a measured slurry concentration, a target bed height, a target packing factor or compression factor and minimum and maximum acceptable values for at least one of target bed height and target packing or compression factor; forcing a movable adapter () along a longitudinal axis of the column () in order to pack the media; detecting when the media bed is consolidated; the control unit () processing the provided data and the information about the consolidated bed height in order to present to the user acceptable bed heights, if there are any, giving acceptable packing or compression factors.

Column packing method

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Uppsala, Sweden

Per Karlberg