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Denator Aktiebolag

Denator Aktiebola

Per Andrén

Karl Sköld

Marcus Svensson

Göran Palmers

Jonas Sävmarker

Mohammadreza Shariatgorji

Luke Odell

Anna Nilsson

The present disclosure concerns use of compounds of formula I, or salts thereof, as reactive matrices for desorption and laser ablation ionization spectrometry. The disclosure further concerns compounds of formula II, or salts thereof, and use of compounds of formula II or III, or salts thereof. 

Pyridinium, quinolinium, acridinium, pyrylium, chromenylium or xanthylizum reactive desorption and/or laser ablation ionization matrices and use thereof

Methods and devices for preparing a biological sample for analysis are described. The biological sample from an organism has at least macromolecule having a primary structure that naturally degrades after the sample is removed from the organism. The method includes causing the biological sample to adopt a shape to permit rapid and uniform heating. The shaped sample is then rapidly and uniformly heated, thereby altering a secondary structure of the macromolecule while preserving its primary structure.

Preparing biological samples for analysis

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Uppsala, Sweden

Per Andrén