Madaus Ag

Laboratoire Medidom Sa

Dr. Madaus & Co.

Oy Extracta Ltd.

Pentti Hietala

Klaus Witthohn

Wolf Grimminger

Helga Zaeske

Alfons Carcasona

Juha H Apajalahti

Hakon Westermarck

Tuomas Walter Westermarck

Maire Jaarma

The present invention provides a process for treating arthritis utilizing substantially pure diacetylrhein having an aloe-emodin content of less than 20 ppm.

Method of preparing diacetyl rhein

The present invention relates to a hydroxy acid or a product containing thereof and a product made containing the same. The invention is characterized by the use of the hydroxy acid as a feed additive, either alone or in combination with other useful compounds or a product containing the same.

Use of hydroxy acid or a product containing the same in animal feed

Sennosides A, B and Al of the formula: ##STR1## which are substantially free from sennosides C, D and Dl, and from aloe-emodin derivatives, are prepared by a process wherein a) a sennoside mixture is reduced to rhein-9-anthrone-8-glucoside and aloe-emodin-9-anthrone-8-glucoside, b) a liquid-liquid partitioning of the compounds obtained is carried out between a polar organic solvent which is only partly miscible with water and an aqueous phase and c) the rhein-9-anthrone-8-glycosides contained after the partitioning in the aqueous phase is again oxidized to the corresponding sennosides and these are recovered.

Method of extracting sennosides A, B and A1

Diacetylrhein which is substantially free of aloe-emodin components, is prepared by a process wherein

The present invention provides a process for obtaining laxative compounds from senna drug, wherein

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Helsinki, Finland

Pentti Hietala