Agensys, Inc.

Peng Yang

Josh Snyder

Faisal Hayat Malik

Ssucheng Jeff Hsu

Claudia Isabel Guevara

Daniel Sousa Pereira

Leslie Renee Butterworth

Karen Jane Meyrick Morrison

Fernando Donate

Antibody drug conjugates (ADC's) that bind to CD37 protein and variants thereof are described herein. CD37 exhibits a distinct and limited expression pattern in normal adult tissue(s), and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention in some embodiments provide a therapeutic composition for the treatment of cancer.

Antibody drug conjugates (ADC) that bind to CD37 proteins

Provided herein are compositions, methods and uses involving antibodies that specifically bind to Nectin-4. Also provided herein are methods for assessing Nectin-4 expression in a sample or a patient and methods for assessing responsiveness of a cancer patient to an anti-cancer therapeutic agent.

Nectin-4 binding proteins and methods of use thereof

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Los Angeles, CA, United States of America

Peng Yang