Xradia, Inc.

Chinese Academy of Sciences

Paul Scherrer Institut

Institute of High Energy Physics

Peiping Zhu

Ziyu Wu

Wenbing Yun

Yuxin Wang

Michael Feser

Andrei V Tkachuk

Qingxi Yuan

Wanxia Huang

Marco Stampanoni

Phase sensitive X-ray imaging methods provide substantially increased contrast over conventional absorption based imaging, and therefore new and otherwise inaccessible information. The use of gratings as optical elements in hard X-ray phase imaging overcomes some of the problems impairing the wider use of phase contrast in X-ray radiography and tomography. To separate the phase information from other contributions detected with a grating interferometer, a phase-stepping approach has been considered, which implies the acquisition of multiple radiographic projections. Here, an innovative, highly sensitive X-ray tomographic phase contrast imaging approach is presented based on grating interferometry, which extracts the phase contrast signal without the need of phase stepping. Compared to the existing phase step approach, the main advantage of this new method dubbed 'reverse projection' is the significantly reduced delivered dose, without degradation of the image quality.

Low dose single step grating based X-ray phase contrast imaging

An x-ray imaging system uses a synchrotron radiation beam to acquire x-ray images and at least one integrated x-ray source. The system has an imaging system including sample stage controlled by linear translation stages, objective x-ray lens, and x-ray sensitive detector system, placed on a fixed optical table and a mechanical translation stage system to switch x-ray sources when synchrotron radiation beam is not available.

X-ray microscope with switchable x-ray source

Mechanism for switching sources in x-ray microscope

Growing community of inventors

Beijing, China

Peiping Zhu