Infinitus (china) Company Ltd.

Overseas Pharmaceuticals, Ltd.

Peipei Wang

Fangli Ma

Minghua Hu

Ming Liang

Xiaoguang Wen

Min Li

Xiaofeng Huang

Dachuan Zhao

Chenliang Zhang

Jun Fan

An ibuprofen controlled-release tablet and a method for preparing same are provided. The controlled-release tablet is composed of a drug-containing immediate-release layer and a drug-containing sustained-release layer, wherein a mass of ibuprofen in the drug-containing sustained-release layer is greater than a mass of ibuprofen in the drug-containing immediate-release layer, and a ratio of the mass of the ibuprofen in the drug-containing sustained-release layer to the mass of the ibuprofen in the drug-containing immediate-release layer is ≤7. The tablet of the present disclosure has an effective analgesic effect for 24 h after administration.

Controlled-release tablet of ibuprofen and method for preparing same

The present invention discloses a Lucidandcomplex polysaccharide having efficacy for regulating tumor microenvironment, whose active components are complexed by Lucidpolysaccharide,polysaccharide andpolysaccharide, the mass proportion ratio of each component is Lucidpolysaccharide 10-250,polysaccharide 1-50,polysaccharide 2-10. The Lucidandcomplex polysaccharide is high in purity and activity, has an efficacy for regulating tumor microenvironment. The present invention also discloses the preparation method of aforesaid Lucidandcomplex polysaccharide, said method is simple, stable and efficient in the process, suitable for industrial production and economic. In addition, the present invention further discloses the use of aforesaid Lucidandpolysaccharide in the preparation of health-care food having efficacy for regulating tumor microenvironment.

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The use of apolysaccharide in the preparation of food supplement having the efficacy of inhibiting colon cancer, whereinpolysaccharide is prepared by a processes including extraction with boiling water, deproteinization, dialysis and ethanol treatment, and has an effect of regulating tumor microenvironment by many pathways involving inhibiting tumor angiogenesis, immunosuppression, anti-oxidation and inhibiting colon cancer fibroblasts.

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Guangzhou, China

Peipei Wang