Cyclerion Therapeutics, Inc.

Triplet Therapeutics, Inc.

Pei Ge

Brian R Bettencourt

Mark G Currie

Paul A Renhowe

James Edward Sheppeck

G-Yoon Jamie Im

Nessan Anthony Bermingham

Jaime L Masferrer

Paul Allan Renhowe

The present disclosure features useful compositions and methods to treat nucleotide repeat expansion disorders, e.g., in a subject in need thereof. In some aspects, the compositions and methods described herein are useful in the treatment of disorders associated with MSH3 activity.

Oligonucleotides for the treatment of nucleotide repeat expansion disorders associated with MSH3 activity

The present disclosure relates to methods, uses, pharmaceutical compositions and kits comprising an sGC stimulator or a pharmaceutically acceptable salt thereof, alone or in combination with one or more additional therapeutic agents, for the treatment of Nonalcoholic Steatohepatitis (NASH).

Use of sGC stimulators for the treatment of nonalcoholic steatohepatitis (NASH)

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Arlington, MA, United States of America

Pei Ge