Esteve Quimica S.a.

Pedro Talavera Escasany

Yolanda Gasanz Guillén

Montserrat Monsalvatje Llagostera

Martí Bartra Sanmartí

Laura Coppi

It comprises a process for the purification of Montelukast, or its salts or its solvates, including any stereoisomer or mixture thereof, which comprises converting Montelukast acid or a solvate thereof, including any stereoisomer or mixtures thereof, into an amine salt selected from the group consisting of tris-(hydroxymethyl)aminomethane, L-(+)-treo-2-amino-1-phenyl-1,3-propanediol, and L-(+)-&#x3b1;-phenylglycinol salt, in the presence of an appropriate solvent. It also comprises novel salts of Montelukast, in particular, tris-(hydroxymethyl)aminomethane, L-(+)-treo-2-amino-1-phenyl-1,3-propanediol, and L-(+)-&#x3b1;-phenylglycinol salts.

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Barcelona, Spain

Pedro Talavera Escasany