Heartware, Inc.

Pedro Grave De Peralta

Neil Voskoboynikov

Carlos Reyes

Veronica Ramos

Zoe N Demou

A method of estimating an amount of work available to be performed by a blood pump implanted in a patient includes calculating a first coordinate value characterizing a volume of blood impelled in the pump and a second coordinate value characterizing a differential pressure across the pump for each of a plurality of flow rate data points of a given cardiac cycle of the patient, each flow rate data point indicative of a flow rate of blood through the pump. An area enclosed by the first and second coordinate values of the plurality of flow rate data points is determined, the determined area being indicative of an amount of work available to be performed by the blood pump.

Pump preload index/indicator

A method of detecting a disruption in a diurnal rhythm of a patient having an implantable blood pump comprising calculating a moving average convergence divergence (MACD) based on power consumed by the implantable blood pump to maintain a constant rotational speed of an impeller of the implantable blood pump and generating an alert when the calculated MACD does not cross a MACD zero line for a predetermined MACD zero line crossing time threshold.

HVAD circadian tracker (PHI+)

The present disclosure provides for methods and devices for determining the probability of a patient's aortic valve being open or closed. In one embodiment, a plurality of flow rate data points are obtained from a blood pump, a portion of the flow rate data points are identified, first and second index values characterizing properties of at least part of the identified portion of the flow rate data points determined using only arithmetic and/or exponentiation operations, and a probability is determined of whether the patient's aortic valve is open or closed based on the first and second index values.

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Miami, FL, United States of America

Pedro Grave De Peralta