Institut Merieux

Paule A Gattel

Jacques C Liautaud

Jean F Pla

Marie-France Makula

Robert A Plan

Andre J Debrus

Michel A Tardy

Jean L Tayot

The process comprises subjecting the hemolyzed blood to a clarification step at a pH of between 4 and 6 in the presence of less than 15% of alcohol, then, after concentration, effecting a chromatography by exchange of anions so as to separate the hemoglobin, the albumin being thereafter eluted. The hemoglobin and the globulins may then be separated out by precipitation with 25% alcohol at a pH of 7. The proteins obtained are in the native state.

Process for preparing the principal proteins of hemolyzed blood in the

Purified albumin is prepared from frozen placenta, placental blood or other hemolyzed blood by the steps of eliminating hemoglobin, eliminating enzymes and eliminating group substances.

Process for the preparation of purified albumin and albumin obtained by

Purified albumin is prepared from an albumin solution containing foreign or denatured proteins by heating the solution in the presence of caprylic acid at a pH of 4.8 - 5.25 at a temperature between 50.degree. - 64.degree. C. The amount of caprylic acid expressed in weight of sodium caprylate is between 15 - 30% by weight of the proteins in said solution.

Process for the preparation of purified albumin by thermocoagulation and

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Caluire, France

Paule A Gattel