Calgene Corporation

Monsanto Technology LLC

Paula C Miller

Kevin E McBride

Lyle Dean Crossland

Tim N Oulmassov

Thomas H Adams

John C Anderson

Barbara A Qurollo

Victoria Gavrias

John M Molyneaux

Jane M Curtis

Thomas J Owen

DNA constructs and other compositions and methods for controlling gene expression in eukaryotic cells and organisms are derived from bacterial quorum sensing systems. One or more cis elements from the luxI promoter ('lux box') or a functionally similar sequence are incorporated in a eukaryotic promoter. A receptor protein from the LuxR family of transcriptional regulators, upon binding an acylated homoserine lactone (AHL) compound, interacts with the lux box, modulating the activity of the promoter.

Control of gene expression in eukaryotic cells

DNA constructs and other compositions and methods for controlling gene expression in eukaryotic cells and organisms are derived from bacterial quorum sensing systems. One or more cis elements from the luxI promoter (&ldquo;lux box&rdquo;) or a functionally similar sequence are incorporated in a eukaryotic promoter. A receptor protein from the LuxR family of transcriptional regulators, upon binding an acylated homoserine lactone (AHL) compound, interacts with the lux box, modulating the activity of the promoter.

Pyrazole compounds with activity as chemical hybridizing agents and methods for synthesis of such compounds are disclosed. These compounds are useful in producing hybrid wheat (,) and other crops.

Production of phosphonopyrazoles

Growing community of inventors

St. Louis, MO, United States of America

Paula C Miller