Qbiotics Pty Ltd

Qbiotics Limited

Ecobiotics Ltd

Johnson & Johnson Consumer Inc.

Johnson & Johnson Consumer Companies, Inc.

Chenango Zero LLC

Paul Warren Reddell

Victoria Anne Gordon

Peter Gordon Parsons

Glen Mathew Boyle

Ryan Moseley

Robert Steadman

Rachael Louise Moses

Jason Kingsley Cullen

Khalid Mahmood

Claude Saliou

Chong Jin Loy

David William Thomas

Lydia Charlotte Powell

Manon F Pritchard

Katja Etel Hill

The present invention relates to methods of treating tumours comprising the localised administration, for example, intratumourally or topically, of an epoxytiglienone compound (as a monotherapy) to cancerous tumours to generate a systemic anticancer abscopal (anenestic) and/or bystander effect.

Method of treating tumours

The present invention relates to tiglien-3-one compounds and their use in methods of treating or preventing protozoal infections, bacterial infections, parasitic infections and cell proliferative disorders. The tiglien-3-one compounds are also used in methods of controlling pests in humans, animals, plants and the environment.

Tiglien-3-one derivatives

The present invention relates to a combination therapy for tumours comprising the administration of an epoxytigliane compound and an immune checkpoint inhibitor. In particular embodiments, there is a method of treating a tumour and/or treating or preventing one or more bystander tumours with the therapy. Pharmaceutical compositions and kits containing epoxytigliane compounds and immune checkpoint inhibitors are also described.

Combination therapy for the treatment or prevention of tumours

The present invention relates to tiglien-3-one compounds and their use in methods of treating or preventing protozoal infections, bacterial infections, parasitic infections and cell proliferative disorders. The tiglien-3-one compounds are also used in methods of controlling pests in humans, animals, plants and the environment

The present invention relates to epoxy-tigliane compounds and their use in promoting wound healing. In particular embodiments, the epoxy-tigliane compounds are epoxy-tigliaen-3-one compounds. Methods of inducing or promoting wound healing as well as methods of reducing scarring and improving cosmetic outcomes upon healing of a wound are described. Compounds and compositions for use in wound healing are also described.

Methods and compositions for wound healing

Provided are methods of lightening skin by applying certain aromatic compounds or botanical extracts containing such compounds to the skin.

Methods of lightening the skin

The invention relates to plant extracts and bioactive molecules derived from the plant genusand their use as antioxidants, antibacterials, anthelmintic, anti-inflammatories, cancer chemopreventatives, food additives and fragrance components in pharmaceuticals, nutraceuticals, foods and cosmetics.

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The present invention relates to spiroketal compounds that are useful in methods of treating or preventing protozoal infections, parasitic infections, bacterial infections, cell proliferative disorders and anti inflammatory disorders. The spiroketal compounds are also useful as immunosuppressive agents, and also in methods of controlling pests.

Growing community of inventors

Yungaburra, Australia

Paul Warren Reddell