Medtronic Physio-control Manufacturing Corporation

Physio-control Manufacturing Corporation

Paul W Schmitt

Douglas Keith Medema

David R Hampton

Tae Hong Joo

Robert A Niskanen

A reduced lead set device (,) that detects and reports the presence of an acute cardiac ischemic condition in a patient includes a reduced set of sensing electrodes (,and,) placed on a patient for acquiring ECG data from the patient. The reduced lead set device evaluates the ECG data on a reduced set of leads by analyzing local features and/or global features of the ECG data. Local features may include local morphological measures such as ST elevation and clinical information on the patient such as age and sex. Global features include projection coefficients calculated from projecting a concatenated vector of heartbeat data onto separate sets of basis vectors that define signal subspaces of ischemic and non-ischemic ECGs. One or more classifiers evaluate the local features and/or global features to determine whether an acute cardiac ischemic condition is detected. The operating point, i.e., sensitivity and specificity, of the reduced lead set device is adjustable. The result of the evaluation is reported to the user of the device.

Reduced lead set device and method for detecting acute cardiac ischemic conditions

A device (,) that detects and reports the presence of an acute cardiac ischemic condition in a patient includes sensing electrodes (,, and,) placed on a patient for acquiring multiple (e.g., twelve) lead ECG data from the patient. The device evaluates the acquired ECG data by analyzing global features derived from the ECG data. Global features include projection coefficients calculated from projecting a concatenated vector of representative heartbeat data onto sets of basis vectors that define an acute cardiac ischemic ECG subspace and a non-ischemic ECG subspace. A classifier evaluates the global features to determine whether an acute cardiac ischemic condition is detected. In a further embodiment of the invention, one or more classifiers evaluate local features, such as local morphological features and patient clinical information, in addition to the global features to determine whether an acute cardiac ischemic condition is detected. The device (,) may be configured with an adjustable sensitivity/specificity operating point. The result of the evaluation is reported to the user of the device.

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Woodinville, WA, United States of America

Paul W Schmitt