Dexcom, Inc.

Advanced Cardiovascular Systems, Inc.

Dex Com, Inc.

Paul V Neale

Peter C Simpson

James H Brauker

Sean T Saint

Mark C Brister

Jason M Halac

Apurv Ullas Kamath

John Michael Gray

Jennifer Blackwell

Maria Noel Brown Wells

James Patrick Thrower

Justen Deering England

Kenneth Pirondini

Mark Douglas Kempkey

Andrew Michael Reinhardt

Sebastian Bohm

Mark Allan Tapsak

Daniel Steven Kline

Michael Robert Mensinger

Jack Pryor

Dubravka Markovic

Robert James Boock

Daniel Shawn Codd

David DeRenzy

Neel Narayan Shah

Randall Scott Koplin

David A Keller

Young Woo Lee

Warren Marc Terry

Patrick John Castagna

Andrew C Joncich

Matthew D Wightlin

James R Petisce

John Charles Barry

Alan Baldwin

Thomas F McGee

Carol Wood Sutherland

Thomas Metzmaker

Louise Emma Van Den Heuvel

David Michael Petersen

Daniel E Apacible

Jason C Wong

Remy E Gagnon

Cameron Brock

Christian Michael Andre George

Jacob S Leach

Neal Davis Johnston

Phong Lieu

Jason Mitchell

Steve Masterson

Aarthi Mahalingam

Thomas Arnold Peyser

Shawn Larvenz

Mark Dervaes

Daiting Rong

Antonio C Llevares

Andrew P Rasdal

Kaushik Aroonkumar Patel

Jeff Jackson

Tom Miller

Kenneth San Vicente

Eric Johnson

Mohammad Ali Shariati

Paul V Goode, Jr

Mark C Shults

John Nolting

Sebastian Böhm

Ryan Everett Schoonmaker

Michael J Estes

Richard Chien Yang

Ted Tang Lee

Disha B Sheth

Arnold Holmquist

Todd Andrew Newhouse

Antonio Ubach

Shanger Wang

Minglian Shi

Jiong Zou

Michael Levozier Moore

Adam J Livingston

John Patrick Majewski

Leah Morta Edra

Victoria E Carr-Brendel

Laura A Martinson

Rathbun K Rhodes

Philip Thomas Pupa

Christopher C Andrews

Timothy Joseph Goldsmith

Joseph J Baker

John A Guerre

Jonathan Bodnar

Nirav Bhatt

Richard S Stack

Andy Edward Denison

Paul F Muller

William Joseph Boyle

Benjamin C Huter

Scott Jason Huter

Samir R Patel

Rathburn K Rhodes

The present invention relates generally to systems and methods for processing, transmitting, and displaying data received from continuous analyte sensor, such as a glucose sensor. In some embodiments, the continuous analyte sensor system comprises a sensor electronics module that includes power saving features. One feature includes a low power measurement circuit that can be switched between a measurement mode and a low power mode, in which charging circuitry continues to apply power to electrodes of a sensor during the low power mode. In addition, the sensor electronics module can be switched between in a low power storage mode higher power operational mode via a switch. The switch can include a reed switch or optical switch, for example. A validation routine can also be implemented to ensure an interrupt signal sent from the switch is valid. The continuous analyte sensor can be physically connected to a sensor electronics module, which is in direct wireless communication with a plurality of different display devices.

Advanced continuous analyte monitoring system

Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.

Integrated delivery device for continuous glucose sensor

Analyte sensors and methods of manufacturing same are provided, including analyte sensors comprising multi-axis flexibility. For example, a multi-electrode sensor systemcomprising two working electrodes and at least one reference/counter electrode is provided. The sensor systemcomprises first and second elongated bodies E, E, each formed of a conductive core or of a core with a conductive layer deposited thereon, insulating layerthat separates the conductive layerfrom the elongated body, a membrane layer deposited on top of the elongated bodies E, E, and working electrodes″ formed by removing portions of the conductive layerand the insulating layer, thereby exposing electroactive surface of the elongated bodies E, E

Analyte sensors and methods of manufacturing same

Sensor systems can be used to measure an analyte concentration. Sensor systems can include a base having a distal side configured to face towards a person's skin. An adhesive can couple the base to the skin. A transcutaneous analyte measurement sensor can be coupled to the base and can be located at least partially in the host. A transmitter can be coupled to the base and can transmit analyte measurement data to a remote device.

Transcutaneous analyte sensor systems and methods

A transcutaneous sensor device configured for continuously measuring analyte concentrations in a host is provided. In some embodiments, the transcutaneous sensor devicecomprises an in vivo portionconfigured for insertion under the skinof the host and an ex vivo portionconfigured to remain above the surface of the skinof the host after sensor insertion of the in vivo portion. The in vivo portion may comprise a tissue piercing elementconfigured for piercing the skinof the host and a sensor bodycomprising a material or support memberthat provides sufficient column strength to allow the sensor body to be pushable in a host tissue without substantial buckling. The ex vivo portionmay be configured to comprise (or operably connect to) a sensor electronics unit and may comprise a mounting unit. Also described here are various configurations of the sensor body and the tissue piercing element that may be used to protect the membrane of the sensor body.

Transcutaneous analyte sensor

Systems for applying a transcutaneous monitor to a person can include a telescoping assembly, a sensor, and a base with adhesive to couple the sensor to skin. The sensor can be located within the telescoping assembly while the base protrudes from a distal end of the system. The system can be configured to couple the sensor to the base by compressing the telescoping assembly.

A system is provided for monitoring glucose in a host, including a continuous glucose sensor that produces a data stream indicative of a host's glucose concentration and an integrated receiver that receives the data stream from the continuous glucose sensor and calibrates the data stream using a single point glucose monitor that is integral with the integrated receiver. The integrated receiver obtains a glucose value from the single point glucose monitor, calibrates the sensor data stream received from the continuous glucose sensor, and displays one or both of the single point glucose measurement values and the calibrated continuous glucose sensor values on the user interface.

Integrated receiver for continuous analyte sensor

The present embodiments relate generally to applicators of on-skin sensor assemblies for measuring an analyte in a host, as well as their method of use and manufacture. In some aspects, an applicator for applying an on-skin sensor assembly to a skin of a host is provided. The applicator includes an applicator housing, a needle carrier assembly comprising an insertion element configured to insert a sensor of the on-skin sensor assembly into the skin of the host, a holder releasably coupled to the needle carrier assembly and configured to guide the on-skin sensor assembly while coupled to the needle carrier assembly, and a drive assembly configured to drive the insertion element from a proximal starting position to a distal insertion position, and from the distal insertion position to a proximal retraction position.

Transcutaneous analyte sensors, applicators therefor, and associated methods

Applicators for applying an on-skin assembly to skin of a host and methods of their use and/or manufacture are provided. An applicator includes an insertion assembly configured to insert at least a portion of the on-skin assembly into the skin of the host, a housing configured to house the insertion assembly, the housing comprising an aperture through which the on-skin assembly can pass, an actuation member configured to, upon activation, cause the insertion assembly to insert at least the portion of the on-skin assembly into the skin of the host, and a sealing element configured to provide a sterile barrier and a vapor barrier between an internal environment of the housing and an external environment of the housing.

Applicators for applying transcutaneous analyte sensors and associated methods of manufacture

Growing community of inventors

San Diego, CA, United States of America

Paul V Neale