Valentx, Inc.

University College London

Ethicon Endo-surgery, Inc.

C. R. Bard, Inc.

Ucl Business Plc

Given Imaging Ltd.

Paul Swain

Joshua Butters

Jonathan Kagan

Lee Guterman

Mitchell Dann

Timothy Noel Mills

Feng Gong

Geoffrey John Brown

T Wade Fallin

Thomas Baldwin

Gerard Von Hoffmann

James Wright

Greg Fluet

Jeffrey Kapec

Kazuna Tanaka

Elisha Rabinovitz

Charles Alexander Mosse

Gary L Long

Gerry D Ouellette

Frank Volke

Martin Benecke

Jeremy Pinchas Gerber

Boaz Aizenshtark

Bertram Manz

William M Tennant, Jr

The present invention provides devices and methods for attachment of an endolumenal gastrointestinal device, such as an artificial stoma device, a gastrointestinal bypass sleeve or other therapeutic or diagnostic device, within a patient's digestive tract. In one application of the invention, an endolumenal bypass sleeve is removably attached in the vicinity of the gastroesophageal junction to treat obesity and/or its comorbidities, such as diabetes. The bypass sleeve may be at least partially deployed by eversion.

Devices and methods for endolumenal gastrointestinal bypass

Methods are disclosed for replaceable attachment of an endoluminal gastrointestinal device, such as an artificial stoma device, a gastrointestinal bypass sleeve device or an attachment cuff, within a patient's digestive tract for treatment of obesity.

Methods of replacing a gastrointestinal bypass sleeve for therapy adjustment

A method for controlling movement of an imaging device in vivo, the method comprising the steps of providing an imaging device having a longitudinal axis and a magnetic component, said device to be inserted into a patient's body; providing a rotating magnetic field outside the patient's body; and advancing the rotating magnetic filed along the patient's body in a desired direction.

System and method for magnetically maneuvering an in vivo device

The present invention provides devices and methods for attachment of an endoluminal gastrointestinal device, such as an artificial stoma device, a gastrointestinal bypass sleeve device or an attachment cuff, within a patient's digestive tract for treatment of obesity.

Devices and methods for attaching an endolumenal gastrointestinal implant

The present invention provides devices and methods for attachment of an endolumenal gastrointestinal device, such as an artificial stoma device, a gastrointestinal bypass sleeve or other therapeutic or diagnostic device, within a patient's digestive tract. In one application of the invention, an endolumenal bypass sleeve is removeably attached in the vicinity of the gastroesophageal junction to treat obesity and/or its comorbidities, such as diabetes. The bypass sleeve may be at least partially deployed by eversion.

Attachment cuff for gastrointestinal implant

Disclosed herein is a method of treating a patient, that includes providing a gastrointestinal sleeve device having an elongate tubular body, with a proximal opening and a distal opening; and positioning the gastrointestinal sleeve device in the patient's digestive tract such that the proximal opening of the tubular body is positioned at the native gastroesophageal junction to receive ingested food and liquids from the patient's esophagus and the distal opening of the tubular body is positioned in the patient's jejunum. The tubular body can then be attached near its proximal opening to the patient at the native gastroesophageal junction.

Methods of transmural attachment in the gastrointestinal system

Attachment system for transmural attachment at the gastroesophageal junction

Cuff and sleeve system for gastrointestinal bypass

A method is described of inserting guide wires into a lumen, for example into the human gastrointestinal tract. A guide wire structure is employed which comprises at least two guide wires each having a leading end portion which terminates in a leading end, the guide wires being connected to one another by a junction at or adjacent their leading ends, the guide wires have a first position in which the leading end portions are substantially parallel to one another, a second position in which the leading end portions are curved, and a third position in which at least one of the leading end portions forms a loop. The guide wire structure is steered through the gastrointestinal tract by selectively advancing or retracting a single guide wire or advancing more than one guide wire simultaneously, according to the path which is required to be followed.

Guide wire structure for insertion into an internal space

A self-propelling device ( ) is adapted to travel through a passage ( ) having walls containing contractile tissue, the device ( ) comprising a body ( ) and at least one contractile tissue-stimulating means for stimulating the walls to urge the device selectively in both a forward direction ( ). The stimulating means may be electrodes ( ), and the passage can be the gut of an animal or human. The device is particularly useful as an enteroscope.

Passage-travelling device

A thread guide device is provided which is adapted to be removably or fixedly mounted on the distal end of an endoscope, or which is an integral part thereof. Alternatively, the device may comprise a head joined to the distal end of an elongate example in the form of longitudinally extending passages, which are laterally spaced from one another. The device permits a knot formed by threads which have passed through the thread guides to be viewed by the endoscope.

Device for use in tying knots

A thread guide device is provided which is adapted to be removably or fixedly mounted on the distal end of an endoscope, or which is an integral part thereof. Alternatively, the device may comprise a head joined to the distal end of an elongate shaft that is slidable within the endoscope. The device has a pair of thread guides, for example in the form of longitudinally extending passages, which are laterally spaced from one another. The device permits a knot formed by threads which have passed through the thread guides to be viewed by the endoscope.

A handle is provided for attachment to a medical endoscope for advancing instrumentalities through the instrument channel of the endoscope. The handle is adapted for use with instrumentalities requiring multiple longitudinal strokes to be performed in a predetermined sequence. A detent mechanism is provided to assure that a first stroke is completed before the next succeeding stroke begins. The invention as disclosed is used to operate an endoscopic sewing machine.

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London, United Kingdom

Paul Swain