General Electric Company

Affibody Ab

Triumf

The University of British Columbia

Triumf, a Joint Venture

Paul Schaffer

Rong Zhang

Faisal Ahmed Syud

Brian Duh-Lan Lee

Elin Gunneriusson

Lars B Abrahmsen

Joachim Feldwisch

Fredrik Frejd

Christofer Lendel

Nina Herne

Peter Brian Iveson

Stefan K Zeisler

Tove Simonsson

François Bénard

Kenneth R Buckley

Jack Mathew Webster

Malin Lindborg

Michael Ernest Marino

Kande Kankanamalage Dayarathna Amarasinghe

Tove Eriksson

Thomas J Ruth

Kuo-shyan Lin

Kenneth Robert Buckley

Thomas J Morley

Victoire Hanemaayer

Milan Vuckovic

Andrew Kyle Henderson Robertson

Hua Yang

Maurice G Dodd

Cornelia Manuela Hoehr

Julius Alexander Klug

Michael S Kovacs

John Valliant

Christopher Lendel

Jennifer Lynne Huntington

Cornelia Hoehr Manuela

Cornelia Manuela

Peter Iveson

Faisal Syud

Lars Abrahmsen

A method of separating actinium and/or radium from proton-irradiated thorium metal. The thorium metal is irradiated to produce isotopes including thorium, actinium and/or radium. The resultant product is dissolved in solution and a selective precipitant is used to precipitate a bulk portion of the thorium. The precipitated thorium can be recovered. Chromatography is carried out on the remaining solution to remove residual thorium and to separate the actinium from the radium.

Systems, apparatus and methods for separating actinium, radium, and thorium

A system for producing technetium-99m from molybdate-100. The system comprises: a target capsule apparatus for housing a Mo-100-coated target plate; a target capsule pickup apparatus for engaging, and delivering the target cell apparatus into a target station apparatus; target station apparatus for receiving and mounting therein the target capsule apparatus. The target station apparatus is engaged with a cyclotron for irradiating the Mo-100-coated target plate with protons. The irradiated target capsule apparatus is transferred to a receiving cell apparatus comprising a dissolution/purification module for receiving therein a proton-irradiated Mo-100-coated target plate. A conveyance conduit infrastructure interconnects: (i) the target capsule pickup apparatus with the target station apparatus, (ii) the target station apparatus and the receiving cell apparatus; and (iii) the receiving cell apparatus and the dissolution/purification module.

Processes, systems, and apparatus for cyclotron production of technetium-99m

Imaging agents comprising an isolated polypeptide conjugated with a radionucleide and a chelator; wherein the isolated polypeptide binds specifically to HER2, or a variant thereof; and methods for preparing and using these imaging agents.

HER2 binders

Imaging agents comprising an isolated polypeptide conjugated with a radionuclide and a chelator; wherein the isolated polypeptide binds specifically to HER2, or a variant thereof; and methods for preparing and using these imaging agents.

Systems and methods for separation or isolation of technetium radioisotopes from aqueous solutions of radioactive or non-radioactive molybdate salts using a polyalkyl glycol-based cross-linked polyether polymer. Some embodiments can be used for the effective purification of radioactive technetium-99m produced from low specific activityMo.

Process and apparatus for separation of technetium-99M from molybdate

Imaging agents that comprise labeled substrates of the cystine/glutamate antiporter of cells, whereby the methods of use comprise introducing the labeled agents into cells via the cystine/glutamate antiporter, which are then reduced to a labeled cysteine, and subsequently detected in the cell.

Labeled molecular imaging agents, methods of making and methods of use

Provided herein are PDGF-R&#x3b2; imaging agents that are polypeptides labeled with a signal generator (e.g., paramagnetic label, a radionuclide, or a fluorophore), wherein the imaging agents bind specifically to PDGFR-&#x3b2;. Also provided are in vivo imaging methods using the imaging agents.

PDGF-R&#x3b2; binders

Growing community of inventors

Vancouver, Canada

Paul Schaffer