Invista North America S.a.r.l.

Inv Nylon Chemicals Americas, LLC

E.i. Dupont De Nemours and Company

Invista Technologies S.a.r.l.

Invista Textiles Limited

Anthony Anton

William P. Parmelee

Diane M. Scholler

Linda H. Sauerbrunn

Paul S. Pearlman

William T. Windley

Peter R. Witt

Paul S Pearlman

Changlin Chen

Gary J Smith

Alex Van Eck Conradie

Gregory S Kirby

Adriana Leonara Botes

Adriana Leonora Botes

Thomas Foo

Alexander Brett Foster

Ron Ozer

Benjamin D Herzog

Ronald James McKinney

William T Windley

James Michael Garner

Sigridur Soley Kristjansdottir

Jonathan Kennedy

Mark Paul Taylor

Peter R Witt

William Paul Parmelee

Diane Marie Scholler

Linda Hoeflich Sauerbrunn

Cristina Serrano Amatriain

Richard Russell Rosin

Yanhui Sun

John Stephen Locke

Vijayendra Kumar

Mariusz Kamionka

Jonathan Paul Combe

Arghya Barman

Alex Conradie

Caroline Tjhen Shibata

Robert B Osborne

Daniel Bawdon

Kenneth J Tadler

Taylor Craig Schulz

Michael James Sargent

Ronald J Mckinney

Hugo Federico Cueto Rojas

William P Parmelee

Diane M Scholler

Linda H Sauerbrunn

Ronald J Mc Kinney

Sigridur S Kristjanstdottir

Sigridur S Kristjansdottir

Disclosed are materials and methods for managing aerobic biosynthesis. The materials include a fermenter system comprising a fermenter, a microorganism provided to the fermenter, and at least two control loops. The methods are directed to measuring and controlling different oxygen concentrations within the fermenter.

Materials and methods for managing aerobic gas fermentation

The present disclosure generally relates to methods for the recovery of amines from aqueous mixtures. In particular, the disclosure relates to methods for separating amines from amine-containing aqueous mixtures by adjusting the pH of the aqueous mixture relative to the highest pKa value for the amines.

Systems and methods for recovering amines and their derivatives from aqueous mixtures

Provided herein are systems and methods for recycling and supplementing off-gas from a gas fed reaction process. The systems and methods are particularly useful for bioprocesses that convert hydrogen gas into one or more biosynthetic products. By maintaining separate hydrogen and oxygen feed gas streams, and forming a recycle gas that introduces a target component of the supply gas to the bioreactor within a target concentration range, the yields, productivities, and safety profiles of the bioprocess can be enhanced.

High hydrogen utilization and gas recycle

Provided herein are methods for increasing the yield of an extracellular product synthesized by an organism cultured in a continuous aerobic fermentation system. The extracellular product yield is increased through the use of an organism modified to decreased production of polyhydroxyalkanoate, to increase production of the extracellular product, and to include promoters that can be inducible in response to nutrient limitation conditions. The extracellular product yield is also increased by operating the continuous fermentation system under particular nutrient limitation conditions. Also provided are non-naturally occurring organisms that have been modified for use with the provided methods, and extracellular products made using the provided methods.

Materials and methods for controlling limitation conditions in product biosynthesis for non-PHB generating species of the generaorand organisms related thereto

The present disclosure describes biocatalytic processes for producing a product, comprising providing an aqueous stream (AS) comprising at least one fermentable substrate and a gaseous stream (GS) comprising at least one of CO/H, H, methane, and/or CO to a fermentation zone, wherein the GS and AS stream are optionally contacted and/or mixed; the fermentation zone comprising at least one organism capable of metabolizing an AS substrate and a GS substrate, wherein the fermentation operates at conditions to mixotrophically metabolize at least one gaseous substrate in the GS and at least one substrate in the AS, producing the product. The present disclosure also describes compositions comprising an AS, a GS, and an organism, wherein the organism or an equivalent or engineered equivalent thereof is a methanotroph or a hydrogen-metabolizing or CO-metabolizing chemolithotrophic organism, and wherein the organism is capable of mixotrophic metabolism of at least one gaseous substrate in the GS and at least one substrate in the AS. The present disclosure also describes a process wherein said fermentation operates at conditions to mixotrophically metabolize at least Hin the gaseous stream and glycerol and lactic acid in the aqueous stream. The present disclosure also describes a system for producing a fermentation or bio-derived product.

Biocatalytic processes and materials for enhanced carbon utilization

Provided herein are methods for generating cellular biomass in continuous aerobic fermentation systems. The biomass yield, and the concentration of polyhydroxyalkanoate within the biomass, are each directed to advantageous levels by operating the continuous fermentation system under particular nutrient limitation conditions. Also provided are biomass produced using the provided methods, and animal feed compositions including the provided biomass.

Materials and methods for controlling PHA biosynthesis in PHA-generating species of the generaorand organisms related thereto

Methods, systems and compositions for producing at least one light-boiling, volatile, organic product using at least a portion of one or more carbon containing substances from a non-biosynthetic process in a biosynthetic process are provided. These methods, systems and compositions are useful in reducing waste treatment load of carbon containing chemical process waste streams.

Materials and methods for the synthesis of carbon products from non-biosynthetic processes and streams

The present disclosure provides methods for controlling oxygen concentration during aerobic biosynthesis, e.g., fermentation. The method may comprise feeding an oxygen-containing gas into a vessel including a fermentation feedstock and reacting the fermentation feedstock with the oxygen-containing gas to form a broth including a gaseous phase dispersed within the broth. The gaseous phase may comprise any unreacted oxygen from the oxygen-containing gas. The method further includes reducing the concentration of the unreacted oxygen in the dispersed gaseous phase to less than the limiting oxygen concentration ('LOC') for flammability before separating the gaseous phase from the fermentation broth. The concentration of the unreacted oxygen in the gaseous phase is reduced by employing oxygen removal schemes or oxygen dilution schemes.

Methods for controlling oxygen concentration during aerobic biosynthesis

Methods for biosynthesising hydrocarbons from a gaseous substrate in non-naturally occurring acetogens as well as non-naturally occurring acetogens for production of hydrocarbons are provided.

Organisms and biosynthetic processes for hydrocarbon synthesis

Nutritive compositions containing an organism having attenuated or no poly(3-hydroxybutyrate) production are provided. These nutritive compositions are useful as feed, such as animal feed and feed additives for ruminants, non-ruminants and aquaculture, etc. Materials and methods for production of these organisms are provided.

Nutritive compositions and methods related thereto

This disclosure relates to strategies for in vivo production of certain carbon-based products, for example, aminated aliphatic compounds having a carbon chain length of C5-C19.

Materials and methods for biosynthetic manufacture of carbon-based chemicals

Provided herein are novel, synthetic polypeptides having, for example, acyl-acyl carrier protein (ACP) thioesterase (TE) activity, including polypeptides that convert pimeloyl-ACP to pimelic acid. In some aspects, the synthetic polypeptides have advantageous enzymatic activity and/or improved substrate specificity relative to a wild type acyl-ACP TE.

Materials and methods for biosynthetic manufacture and utilization of synthetic polypeptides, and products therefrom

This document describes a process for the high purity and high concentration recovery of monovalent products via continuous ion exchange from aqueous solution for further down-stream purification.

Materials and methods for the selective recovery of monovalent products from aqueous solutions using continuous ion exchange

Embodiments of the present invention relate to methods for the biosynthesis of di- or trifunctional C7 alkanes in the presence of isolated enzymes or in the presence of a recombinant host cell expressing those enzymes. The di- or trifunctional C7 alkanes are useful as intermediates in the production of nylon-7, nylon-7,x, nylon-x,7, and polyesters.

Bioconversion process for producing nylon-7, nylon-7,7 and polyesters

Growing community of inventors

Thornton, PA, United States of America

Paul S Pearlman